ArticleJournal of medical Internet research2025
Digital Isolation and Dementia Risk in Older Adults: Longitudinal Cohort Study.
Article in Journal of medical Internet research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Advancing Remote Monitoring for Patients With Alzheimer Disease and Related Dementias: Systematic Review.JMIR aging · 2025Pooled it
- Health-Related Digital Engagement and Incident Stroke Among Older Adults: Prospective Cohort Study.Journal of medical Internet research · 2026Article
- Virtual Dementia in the Digital Age: Neurocognitive Mechanisms, Behavioural Impact and Public Health Implications of Technology Overuse.Annals of neurosciences · 2026Review
- Digital Engagement and Cognitive Function Among Older Adults in China: Cross-Sectional Questionnaire Study and Moderated Mediation Model Analysis.Journal of medical Internet research · 2026Article
- Quantitative evaluation of China's smart aging healthcare policy under the background of silver economy development: based on PMC model.Frontiers in public health · 2026Article
- Digital Isolation and Depression Risk in Older Adults Using the National Health and Aging Trends Study Database: 8-Year Longitudinal Study.JMIR aging · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDementia poses a significant global health challenge, characterized by progressive cognitive decline and functional impairment. With the aging global population, dementia prevalence is projected to surge, reaching an estimated 153 million cases by 2050. While the impact of traditional social isolation on dementia risk has been extensively studied, the influence of digital isolation, a phenomenon unique to the digital age, remains underexplored.
objectiveThis study aimed to investigate the association between digital isolation and dementia risk among older adults, hypothesizing that higher levels of digital isolation significantly increase the risk of developing dementia.
methodsWe conducted a longitudinal cohort study using data from the National Health and Aging Trends Study (NHATS), analyzing 8189 participants aged 65 years and older from the 3rd (2013) to the 12th wave (2022). Digital isolation was quantified using a composite digital isolation index, derived from participants' usage of digital devices, electronic communication, internet access, and engagement in online activities. Participants were stratified into low isolation and moderate to high isolation groups. Dementia incidence was assessed using cognitive tests and proxy reports. Cox proportional hazards models were used to estimate the association between digital isolation and dementia risk, adjusting for potential confounders including sociodemographic factors, baseline health conditions, and lifestyle variables.
resultsThe moderate to high isolation group demonstrated a significantly elevated risk of dementia compared with the low isolation group. In the discovery cohort, the adjusted hazard ratio (HR) was 1.22 (95% CI 1.01-1.47, P=.04), while the validation cohort showed an HR of 1.62 (95% CI 1.27-2.08, P<.001). The pooled analysis across both cohorts revealed an adjusted HR of 1.36 (95% CI 1.16-1.59, P<.001). Kaplan-Meier curves corroborated a higher incidence of dementia in the moderate to high isolation group.
conclusionsOur findings indicate that digital isolation is a significant risk factor for dementia among older adults. This study underscores the importance of digital engagement in mitigating dementia risk and suggests that promoting digital literacy and access to digital resources should be integral components of public health strategies aimed at dementia prevention.
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