Evidence map›Paper›PMID 39969790›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025

Predicting outcomes in persistent atrial fibrillation: the impact of surface ECG f-wave amplitude following pulmonary vein isolation.

Aruran Baskaralingam, Matteo Marchetti, Jorge Solana-Munoz, Cheryl Teres, Mathieu Le Bloa, Alessandra Pia Porretta, Giulia Domenichini, Ciro Ascione, Laurent Roten, Sven Knecht and 5 more

Abstract read
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. How to interpret fibrillatory wave amplitude in patients receiving pulmonary vein isolation for atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
  2. Article
  3. F-wave vector magnitude predicts recurrence after catheter ablation of atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Aruran BaskaralingamService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland. aruran006@hotmail.com.ORCID http://orcid.org/0009-0008-9947-085X
Matteo MarchettiService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Jorge Solana-MunozService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Cheryl TeresService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Mathieu Le BloaService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Alessandra Pia PorrettaService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Giulia DomenichiniService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Ciro AscioneService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Laurent RotenDepartment of Cardiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Sven KnechtDepartment of Cardiology, University Hospital of Basel, Basel, Switzerland.
Michael KühneDepartment of Cardiology, University Hospital of Basel, Basel, Switzerland.
Christian SticherlingDepartment of Cardiology, University Hospital of Basel, Basel, Switzerland.
Patrizio PascaleService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Etienne PruvotService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.
Adrian LucaService of Cardiology, Lausanne University Hospital, University of Lausanne, Rue du Bugnon 46, CH-1011, Lausanne, Vaud, Switzerland.

Funding

Commission for Technology and Innovation (CTI), Switzerland. 18265.1 PFLS-LS
6 · The paper itself

Abstract

backgroundFibrillatory wave amplitude (fWA) on 12-lead ECG predicts the outcome of ablation in atrial fibrillation (AF). We hypothesized that changes in fWA following wide circumferential isolation of pulmonary veins (WPVI) in persistent AF (peAF) is a better predictor of ablation outcome compared to baseline fWA.

methodsEighty-nine patients (sustained peAF 7 ± 7 months) underwent a first-time WPVI. Sixty-second ECG signals devoid of QRST waves were recorded at baseline and at the end of the WPVI (endWPVI). fWA for each ECG lead and mean fWA (meanfWA) across the 12-lead ECG were computed. Patients with recurrence after the index WPVI underwent a redo to ensure complete PVI. The primary endpoint was long-term AF freedom OFF antiarrhythmics drugs (AADs) after one or two WPVI (SUCCESS group). The FAILURE group was defined as AF recurrence post-redo.

resultsOver a mean follow-up of 35 ± 10 months, freedom from AF OFF AADs was achieved in 61% (SUCCESS group), while 29% had AF recurrence after redo WPVI (FAILURE group). The SUCCESS group showed significantly higher fWA values in ECG leads V

conclusionLow fWA values and a significant reduction in fWA following WPVI are associated with a high risk of AF recurrence in patients with peAF.

Indexed as

Atrial FibrillationCatheter AblationElectrocardiographyPulmonary VeinsAgedFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRecurrenceTreatment OutcomeAtrial fibrillationF-wave amplitudePulmonary vein isolationSurface electrocardiogram

Identifiers

PMID39969790
PMCPMC12399694

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.