Evidence map›Paper›PMID 39969623›Full record

SynthesisClinical oral investigations2025

Exploring a decade of deep learning in dentistry: A comprehensive mapping review.

Fatemeh Sohrabniya, Sahel Hassanzadeh-Samani, Seyed AmirHossein Ourang, Bahare Jafari, Golnoush Farzinnia, Fatemeh Gorjinejad, Azadeh Ghalyanchi-Langeroudi, Hossein Mohammad-Rahimi, Antonin Tichy, Saeed Reza Motamedian and 1 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fatemeh Sohrabniya *ITU/WHO/WIPO Global Initiative on Artificial Intelligence for Health - Dental Diagnostics and Digital Dentistry, Geneva, Switzerland.
Sahel Hassanzadeh-Samani *ITU/WHO/WIPO Global Initiative on Artificial Intelligence for Health - Dental Diagnostics and Digital Dentistry, Geneva, Switzerland.
Seyed AmirHossein OurangDentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Bahare JafariDivision of Orthodontics, The Ohio State University, Columbus, OH, 43210, USA.
Golnoush FarzinniaCollege of Dentistry, University of Saskatchewan, Saskatoon, SK, Canada.
Fatemeh GorjinejadITU/WHO/WIPO Global Initiative on Artificial Intelligence for Health - Dental Diagnostics and Digital Dentistry, Geneva, Switzerland.
Azadeh Ghalyanchi-LangeroudiMedical Physics & Biomedical Engineering Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Hossein Mohammad-RahimiDepartment of Dentistry and Oral Health, Aarhus University, Vennelyst Boulevard 9, Aarhus C, 8000, Aarhus, Denmark.
Antonin TichyDepartment of Conservative Dentistry and Periodontology, LMU University Hospital, LMU Munich, Munich, Germany.
Saeed Reza MotamedianDentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. drmotamedian@gmail.com.
Falk SchwendickeDepartment of Conservative Dentistry and Periodontology, LMU University Hospital, LMU Munich, Munich, Germany.

Funding

World Health Organization 001
6 · The paper itself

Abstract

objectivesArtificial Intelligence (AI), particularly deep learning, has significantly impacted healthcare, including dentistry, by improving diagnostics, treatment planning, and prognosis prediction. This systematic mapping review explores the current applications of deep learning in dentistry, offering a comprehensive overview of trends, models, and their clinical significance. MATERIALS AND

methodsFollowing a structured methodology, relevant studies published from January 2012 to September 2023 were identified through database searches in PubMed, Scopus, and Embase. Key data, including clinical purpose, deep learning tasks, model architectures, and data modalities, were extracted for qualitative synthesis.

resultsFrom 21,242 screened studies, 1,007 were included. Of these, 63.5% targeted diagnostic tasks, primarily with convolutional neural networks (CNNs). Classification (43.7%) and segmentation (22.9%) were the main methods, and imaging data-such as cone-beam computed tomography and orthopantomograms-were used in 84.4% of cases. Most studies (95.2%) applied fully supervised learning, emphasizing the need for annotated data. Pathology (21.5%), radiology (17.5%), and orthodontics (10.2%) were prominent fields, with 24.9% of studies relating to more than one specialty.

conclusionThis review explores the advancements in deep learning in dentistry, particulary for diagnostics, and identifies areas for further improvement. While CNNs have been used successfully, it is essential to explore emerging model architectures, learning approaches, and ways to obtain diverse and reliable data. Furthermore, fostering trust among all stakeholders by advancing explainable AI and addressing ethical considerations is crucial for transitioning AI from research to clinical practice. CLINICAL RELEVANCE: This review offers a comprehensive overview of a decade of deep learning in dentistry, showcasing its significant growth in recent years. By mapping its key applications and identifying research trends, it provides a valuable guide for future studies and highlights emerging opportunities for advancing AI-driven dental care.

Indexed as

Deep LearningDentistryHumansArtificial intelligenceDeep learningDentistryDiagnostic imagingNeural networks

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.