Evidence map›Paper›PMID 39969592›Full record

ArticleLasers in medical science2025

Antimicrobial photodynamic therapy using gold nanoparticles conjugated with 1,9-dimethyl-methylene blue for treating Staphylococcus skin infections.

Anildo Alves de Brito Júnior, Pedro Jorge Louro Crugeira, Wellington Luis Reis Costa, Andressa Vollono Barbosa, Susana Carla Pires Sampaio de Oliveira, Maria Cristina Teixeira Cangussu, Jean Nunes Dos Santos, Juliana Monteiro Azevedo, Antonio Luiz Barbosa Pinheiro

Abstract read
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anildo Alves de Brito JúniorFederal University of Bahia, Salvador, Brazil.
Pedro Jorge Louro CrugeiraFederal University of Bahia, Salvador, Brazil.
Wellington Luis Reis CostaFederal University of Bahia, Salvador, Brazil.
Andressa Vollono BarbosaFederal University of Bahia, Salvador, Brazil.
Susana Carla Pires Sampaio de OliveiraFederal University of Bahia, Salvador, Brazil.
Maria Cristina Teixeira CangussuFederal University of Bahia, Salvador, Brazil.
Jean Nunes Dos SantosFederal University of Bahia, Salvador, Brazil.
Juliana Monteiro AzevedoFederal University of Bahia, Salvador, Brazil.
Antonio Luiz Barbosa PinheiroFederal University of Bahia, Salvador, Brazil. albp@ufba.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 304279/2018-8Conselho Nacional de Desenvolvimento Científico e Tecnológico 309702/2021-6Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88887.670810/2022-00OleaChain project NORTE-06-3559-FSE-000188
6 · The paper itself

Abstract

This study aims to assess the effectiveness of Antimicrobial Photodynamic Therapy (aPDT) using phenothiazine photosensitizer (PS) combined with gold nanoparticles (DMMB-AuNPs) in treating S. aureus-contaminated wounds on the dorsum of rats. Twelve Wistar rats were divided into four groups: Control, LED, DMMB-AuNPs, and DMMB-AuNPs + LED. DMMB-AuNPs were prepared using DMMB (300 ng/mL) and 5 nm diameter AuNPs (~ 5.5E + 13 particles/mL). The light source was a red LED (12 J/cm

Indexed as

GoldMetal NanoparticlesMethylene BluePhotochemotherapyPhotosensitizing AgentsStaphylococcal Skin InfectionsAnimalsMaleRatsRats, WistarStaphylococcus aureusGoldMethylene BluePhotosensitizing AgentsNanotechnologyPhotodynamic inactivationStaphylococcus aureusWound

Identifiers

PMID39969592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.