Evidence map›Paper›PMID 39969563›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2025

Risk factors for residual neuropathic pain using specific screening tools in postoperative patients with ossification of the posterior longitudinal ligament of the cervical spine.

Shinsuke Ikeda, Masayuki Miyagi, Gen Inoue, Toshitaka Yoshii, Satoru Egawa, Kenichiro Sakai, Masahiko Takahata, Tsutomu Endo, Shunji Tsutsui, Masao Koda and 13 more

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Shinsuke IkedaDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0375, Japan.
Masayuki MiyagiDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0375, Japan. masayuki008@aol.com.
Gen InoueDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0375, Japan.
Toshitaka YoshiiDepartment of Orthopedic Surgery, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo Ward, Tokyo, 113-8519, Japan.
Satoru EgawaDepartment of Orthopedic Surgery, Institute of Science Tokyo, 1-5-45 Yushima, Bunkyo Ward, Tokyo, 113-8519, Japan.
Kenichiro SakaiDepartment of Orthopedic Surgery, Saiseikai Kawaguchi General Hospital, 5-11-5 Nishikawaguchi, Kawaguchishi, Saitama, 332-8558, Japan.
Masahiko TakahataDepartment of Orthopaedic Surgery, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu-Machi, Shimotsuga-Gun, Tochigi, 321-0293, Japan.
Tsutomu EndoDepartment of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Sapporo, 060-8638, Japan.
Shunji TsutsuiDepartment of Orthopaedic Surgery, Wakayama Medical University, 811-1 Kimiidera, Wakayama, 641-8509, Japan.
Masao KodaDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Hiroshi TakahashiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.
Satoshi KatoDepartment of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, 13-1 Takara-Machi, Kanazawa, 920-8641, Japan.
Kanji MoriDepartment of Orthopaedic Surgery, Shiga University of Medical Science, Tsukinowa-Cho, Seta, Otsu, Shiga, 520-2192, Japan.
Hideaki NakajimaDepartment of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka Shimoaizuki, Eiheiji-Cho, Yoshida-Gun, Fukui, 910-1193, Japan.
Takeo FuruyaDepartment of Orthopedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo Ward, Chiba, Chiba, 260-0856, Japan.
Satoshi MakiDepartment of Orthopedic Surgery, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo Ward, Chiba, Chiba, 260-0856, Japan.
Yoshiharu KawaguchiDepartment of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, Toyama, 930-0194, Japan.
Norihiro NishidaDepartment of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube City, Yamaguchi Prefecture, 755-8505, Japan.
Kazuo KusanoDepartment of Orthopedic Surgery, Kudanzaka Hospital, 1-6-12 Kudanminami, Chiyodaku, Tokyo, 102-0074, Japan.
Hiroaki NakashimaDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho, Showa Ward, Nagoya, Aichi, 466-8550, Japan.
Yuji YokozekiDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0375, Japan.
Masashi TakasoDepartment of Orthopaedic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami Ward, Sagamihara, Kanagawa, 252-0375, Japan.
Masashi YamazakiDepartment of Orthopaedic Surgery, Institute of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8575, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAgeing, long illness duration, and poor preoperative Japanese Orthopaedic Association (JOA) score were reported to be risk factors for residual pain after cervical ossification of the posterior longitudinal ligament (cOPLL). In this study, we focused on residual neuropathic pain (NeP) and aimed to elucidate risk factors for residual NeP after cOPLL.

methodsTotal of 234 patients who underwent cOPLL surgery were included. NeP was evaluated using painDETECT (PDQ) and Spine painDETECT (SPDQ) questionnaires. Score of ≥ 13 / ≥ 0 was defined as NeP for PDQ/SPDQ. Patient backgrounds factors, preoperative radiographic factors and surgical factors were reviewed, and comparisons between the NeP(+) and NeP(-) groups were made. Independent risk factors for residual NeP were evaluated using multiple logistic regression analysis.

resultsPrevalence of residual NeP after cOPLL was 22.6% on PDQ and 55.1% on SPDQ. Preoperative JOA score was significantly lower in the NeP(+) group for PDQ compared with that in the NeP(-) group. Additionally, cervical lordosis angle was significantly lower in the NeP(+) group for SPDQ compared with that in the NeP(-) group. Following multiple logistic regression analysis, poor preoperative JOA score was identified as a risk factor for NeP on the PDQ. Poor preoperative JOA score and low cervical lordosis angle were identified as risk factors using the SPDQ.

conclusionsWe found high prevalence of residual NeP after cOPLL. Patients with a poor preoperative JOA score and low cervical lordosis angle might be at risk for residual NeP after surgery evaluated by PDQ or SPDQ and should be monitored with greater care after surgery.

Indexed as

Cervical VertebraeNeuralgiaOssification of Posterior Longitudinal LigamentPostoperative ComplicationsAdultAgedFemaleHumansMaleMiddle AgedPain MeasurementRetrospective StudiesRisk FactorsNeuropathic painOssification of the posterior longitudinal ligamentpainDETECT QuestionnairePostoperative residual painSpine painDETECT Questionnaire

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.