Evidence map›Paper›PMID 39969391›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2025

A Universal Strategy to Mitigate Microphase Separation via Cellulose Nanocrystal Hydration in Fabricating Strong, Tough, and Fatigue-Resistant Hydrogels.

Siheng Wang, Zhengyang Yu, Xia Sun, Mahyar Panahi-Sarmad, Pu Yang, Penghui Zhu, Yeling Zhu, He Liu, Feng Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Harnessing Phase Separation for the Development of High-Performance Hydrogels.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Harnessing Chain Mobility via Protonation for Tough and Isotropic Hydrogel.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Siheng WangKey Laboratory of Biomass Energy and Material, Jiangsu Province; Key Laboratory of Chemical Engineering of Forest Products, National Forestry and Grassland Administration, National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, 210042, China.
Zhengyang YuSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Xia SunSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Mahyar Panahi-SarmadSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Pu YangSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Penghui ZhuSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
Yeling ZhuSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.
He LiuKey Laboratory of Biomass Energy and Material, Jiangsu Province; Key Laboratory of Chemical Engineering of Forest Products, National Forestry and Grassland Administration, National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, Nanjing, 210042, China.
Feng JiangSustainable Functional Biomaterials Laboratory, Bioproducts Institute, Department of Wood Science, University of British Columbia, Vancouver, BC, V6T 1Z4, Canada.ORCID https://orcid.org/0000-0003-2497-9922

Funding

Canada Foundation for Innovation 37517Canada Research Chairs 231928China Scholarship Council 202203270012Forestry Science and Technology Innovation and Extension Project of Jiangsu Province LYKJ[2021]04
6 · The paper itself

Abstract

As a common natural phenomenon, phase separation is exploited for the development of high-performance hydrogels. Using supersaturated salt to create microphase-separated hydrogels with strengthened mechanical properties has gained widespread attention. However, such strengthened hydrogel loses its intrinsic flexibility, making the phase separation strategy unsuitable for the fabrication of stretchable and tough hydrogels. Here, a phase-engineering design strategy is introduced to produce stretchable yet tough hydrogels using supersaturated NaAc salt, by leveraging the hydration effect of cellulose nanocrystal (CNC) to mitigate microphase separation. The CNC-mitigated microphase-separated hydrogel presents unprecedented mechanical properties, for example, tensile strength of 1.8 MPa with a fracture strain of 4730%, toughness of 43.1 MJ m

Indexed as

cellulose nanocrystalfatigue‐resistantmicrophase separationsodium acetatestrong tough hydrogel

Identifiers

PMID39969391
PMCPMC11837898

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.