Evidence map›Paper›PMID 39969280›Full record

ArticleMicrobial genomics2025

Genomic insights into the beneficial potential of

Pierre Marie Kaktcham, Magdalena Kujawska, Edith Marius Foko Kouam, Laverdure Tchamani Piame, Michele Letitia Tchabou Tientcheu, Julia Mueller, Angela Felsl, Bastian-Alexander Truppel, François Zambou Ngoufack, Lindsay J Hall

Abstract read
In one paragraph

Article in Microbial genomics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Genomic Characterization and Safety Evaluation ofAntibiotics (Basel, Switzerland) · 2025
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pierre Marie KaktchamResearch Unit of Biochemistry of Medicinal Plants, Food Science and Nutrition (URBPMAN) - Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon. P.O Box 67, Dschang, Cameroon.
Magdalena KujawskaIntestinal Microbiome, ZIEL - Institute for Food & Health, Technical University of Munich, Freising, 85354, Germany.
Edith Marius Foko KouamDepartment of Physiological Sciences and Biochemistry, Faculty of Medicine and Pharmaceutical Sciences, University of Dschang, Dschang, Cameroon.
Laverdure Tchamani PiameResearch Unit of Biochemistry of Medicinal Plants, Food Science and Nutrition (URBPMAN) - Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon. P.O Box 67, Dschang, Cameroon.
Michele Letitia Tchabou TientcheuResearch Unit of Biochemistry of Medicinal Plants, Food Science and Nutrition (URBPMAN) - Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon. P.O Box 67, Dschang, Cameroon.
Julia MuellerIntestinal Microbiome, ZIEL - Institute for Food & Health, Technical University of Munich, Freising, 85354, Germany.
Angela FelslIntestinal Microbiome, ZIEL - Institute for Food & Health, Technical University of Munich, Freising, 85354, Germany.
Bastian-Alexander TruppelIntestinal Microbiome, ZIEL - Institute for Food & Health, Technical University of Munich, Freising, 85354, Germany.
François Zambou NgoufackResearch Unit of Biochemistry of Medicinal Plants, Food Science and Nutrition (URBPMAN) - Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon. P.O Box 67, Dschang, Cameroon.
Lindsay J HallIntestinal Microbiome, ZIEL - Institute for Food & Health, Technical University of Munich, Freising, 85354, Germany.

Funding

Wellcome Trust
6 · The paper itself

Abstract

A healthy early-life gut microbiota plays an important role in maintaining immediate and long-term health. Perturbations, particularly in low- to middle-income communities, are associated with increased infection risk. Thus, a promising avenue for restoring a healthy infant microbiota is to select key beneficial bacterial candidates from underexplored microbiomes for developing new probiotic-based therapies. This study aimed to recover bifidobacteria and lactic acid bacteria from the faeces of healthy Cameroonian infants and unravel the genetic basis of their beneficial properties. Faecal samples were collected from 26 infants aged 0-5 months recruited in Dschang (Cameroon). Recovered bacterial isolates were subjected to whole-genome sequencing and

Indexed as

BifidobacteriumEnterococcusGastrointestinal MicrobiomeCameroonFecesFemaleGenome, BacterialGenomicsHumansInfantInfant, NewbornMalePhylogenyProbioticsWhole Genome SequencingbifidobacteriaEnterococcusfunctional genomicsprobioticssafetywhole-genome sequencing

Identifiers

PMID39969280
PMCPMC11840169

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.