Evidence map›Paper›PMID 39969279›Full record

ArticleRadiology. Artificial intelligence2025

Deep Learning-based Brain Age Prediction Using MRI to Identify Fetuses with Cerebral Ventriculomegaly.

Hyuk Jin Yun, Han-Jui Lee, Sungmin You, Joo Young Lee, Jerjes Aguirre-Chavez, Lana Vasung, Hyun Ju Lee, Tomo Tarui, Henry A Feldman, P Ellen Grant and 1 more

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hyuk Jin Yun *Fetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0002-9876-314X
Han-Jui Lee *Fetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0002-9303-7165
Sungmin YouFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0002-2144-9523
Joo Young LeeFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.
Jerjes Aguirre-ChavezFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0003-1191-1144
Lana VasungFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0003-0172-3174
Hyun Ju LeeFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0009-0009-1123-0702
Tomo TaruiMother Infant Research Institute, Tufts Medical Center, Boston, Mass.ORCID 0000-0003-3860-7062
Henry A FeldmanFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0002-1748-0894
P Ellen GrantFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0003-1005-4013
Kiho ImFetal Neonatal Neuroimaging and Developmental Science Center, Harvard Medical School, Boston, Mass.ORCID 0000-0002-9239-8970

Funding

Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
Genetic and Hemodynamic Effects on Prenatal Cortical Development in Congenital Heart DiseaseR01NS114087 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI IM, KIHO · 2020 to 2024
$2.8M
Fetal MRI: robust self-driving brain acquisition and body movement quantificationR01EB032708 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2022 to 2025
$2.8M
Measuring cortical plate and subplate thickness in the human fetal brain from magnetic resonance imagesR01EB031170 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI IM, KIHO · 2021 to 2025
$2.5M
Prenatal diagnosis of brain malformations: Improving assessment of prognosisK23HD079605 · NICHD · TUFTS MEDICAL CENTER · PI TARUI, TOMO · 2015 to 2019
$767k
NIBIB NIH HHS R01 EB031170NIBIB NIH HHS R01 EB032708NICHD NIH HHS K23 HD079605NICHD NIH HHS R01 HD100009NINDS NIH HHS R01 NS114087
6 · The paper itself

Abstract

Fetal ventriculomegaly (VM) and its severity and associated central nervous system (CNS) abnormalities are important indicators of high risk for impaired neurodevelopmental outcomes. Recently, a novel fetal brain age prediction method using a two-dimensional (2D) single-channel convolutional neural network (CNN) with multiplanar MRI sections showed the potential to detect fetuses with VM. This study examines the diagnostic performance of a deep learning-based fetal brain age prediction model to distinguish fetuses with VM (

Indexed as

BrainDeep LearningHydrocephalusMagnetic Resonance ImagingPrenatal DiagnosisFemaleGestational AgeHumansNeural Networks, ComputerPregnancyBrain/Brain StemConvolutional Neural Network (CNN)Deep Learning AlgorithmsFetusMachine LearningMR-Fetal (Fetal MRI)Supervised Learning

Identifiers

PMID39969279
PMCPMC11950871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.