Evidence map›Paper›PMID 39969203›Full record

ArticleOncotarget2025

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters' model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane.

Ana Chor, Hélio Dos Santos Dutra, Marcos Lopes Dias, Raquel Pires Gonçalves, Christina Maeda Takiya, Alexandre Malta Rossi, Marcos Farina

Abstract read
In one paragraph

Article in Oncotarget, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana Chor *Biomineralization Laboratory, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.
Hélio Dos Santos DutraUniversity Hospital, Bone Marrow Transplantation Unit, Federal University of Rio de Janeiro, Rio de Janeiro 21941-617, Brazil.
Marcos Lopes DiasCatalysis Laboratory for Polymerization, Recycling and Biodegradable Polymers, Institute of Macromolecules Professor Eloisa Mano, Federal University of Rio de Janeiro, Rio de Janeiro 21941-598, Brazil.
Raquel Pires GonçalvesCatalysis Laboratory for Polymerization, Recycling and Biodegradable Polymers, Institute of Macromolecules Professor Eloisa Mano, Federal University of Rio de Janeiro, Rio de Janeiro 21941-598, Brazil.
Christina Maeda Takiya *Immunopathology Laboratory, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro 20941-902, Brazil.
Alexandre Malta RossiDepartment of Condensed Matter, Applied Physics and Nanoscience, Brazilian Center for Research in Physics, Rio de Janeiro 22290-180, Brazil.
Marcos FarinaBiomineralization Laboratory, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro 21941-902, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical parameters of leukogram and weight were analyzed in animal models before and after seven days of 5-FU infusions. A comparison of leukograms before and after 5-FU administrations was analyzed. The results showed a significant difference (

Indexed as

Antimetabolites, AntineoplasticFluorouracilLactic AcidMembranes, ArtificialPolyglycolic AcidStomatitisWeight LossAnimalsDisease Models, AnimalMaleMesocricetusPolylactic Acid-Polyglycolic Acid CopolymerRegenerationAntimetabolites, AntineoplasticFluorouracilLactic AcidMembranes, ArtificialPolyglycolic AcidPolylactic Acid-Polyglycolic Acid Copolymerleukopeniaoral mucositisPLGA dressingregenerationweight loss

Identifiers

PMID39969203
PMCPMC11837862

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.