New insights into the testicular tropism of porcine reproductive and respiratory syndrome virus.

Kassandra Durazo-Martínez, Fernando A Osorio, Gustavo Delhon, Jesús Hernández, Hiep L X Vu

Abstract read

In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kassandra Durazo-MartínezNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0009-0000-9106-2909

Fernando A OsorioNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.

Gustavo DelhonSchool of Veterinary Medicine and Biomedical Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.

Jesús HernándezLaboratorio de Inmunología, Centro de Investigación en Alimentación y Desarrollo A.C. (CIAD, A.C.), Hermosillo, Sonora, Mexico.

Hiep L X VuNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, Nebraska, USA.ORCID 0000-0001-8084-4358

Funding

USDA | National Institute of Food and Agriculture (NIFA) 2023-67015-39657,1020749

6 · The paper itself

Abstract

Porcine reproductive and respiratory syndrome virus (PRRSV) has a restricted host specificity, primarily infecting porcine macrophages. Notably, an exception to such macrophage-restricted tropism has been observed in sexually active boars, where the virus infects and induces apoptosis in the germinal epithelium, resulting in viral dissemination in the ejaculate. Whether this phenomenon occurs in prepubertal animals remains unclear. In this study, we isolated spermatogonia stem cells (SSCs) from neonatal pigs and cultured them

Indexed as

Porcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusTestisViral TropismAnimalsCells, CulturedMacrophagesMacrophages, AlveolarMaleSpermatogoniaSwineVirus ReplicationPRRSVspermatogonia stem cellsswine virusestesticular tropism

Identifiers

PMID39969185

DOI10.1128/spectrum.02964-24

PMCPMC11960452

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.