Evidence map›Paper›PMID 39969046›Full record

Observational studyCNS spectrums2025

Attenuated mental symptoms in the general population: first data from the observational cross-sectional ATTENTION study in Greece.

Michaela Koummati, Jelena Vrublevska, Marc De Hert, Allan H Young, Paolo Fusar-Poli, Rajiv Tandon, Afzal Javed, Konstantinos N Fountoulakis

Abstract readObservational Study
In one paragraph

Observational study in CNS spectrums, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michaela Koummati3rd Department of Psychiatry School of Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki, Greece.ORCID 0009-0003-6812-7307
Jelena VrublevskaUniversity of Latvia, Faculty of Medicine and Life Sciences and Riga Centre of Psychiatry and Addiction Disorders, Riga, Latvia.
Marc De HertUniversity Psychiatric Centre Katholieke Universiteit Leuven, Kortenberg, Belgium.ORCID 0000-0003-4255-5920
Allan H YoungDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, South London, UK.ORCID 0000-0003-2291-6952
Paolo Fusar-PoliEarly Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, King's College London, UK.
Rajiv TandonDepartment of Psychiatry, WMU Homer Stryker School of Medicine, Kalamazoo, MI49008, USA.
Afzal JavedInstitute of Applied Health Research, University of Birmingham, UK.
Konstantinos N Fountoulakis3rd Department of Psychiatry School of Medicine, Faculty of Health Sciences Aristotle University of Thessaloniki, Greece.ORCID 0000-0001-5503-0811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been reported that abnormal experiences could be common in the general "healthy" population, with the vast majority of individuals never proceeding to manifest a frank mental disorder.

aimsThis study aimed to quantify subthreshold psychiatric symptoms in the general population.

methodsThe protocol included clinicodemographic data and a mental symptoms questionnaire, and additionally, the CES-D, STAI-S, RASS, and the GloDiS to assess depression, anxiety, suicidality, and functional impairment, respectively. The data were collected online and anonymously from 1504 persons (75.66% females; 23.73% males). Descriptive statistics, risk ratios, and factor analysis were utilized.

resultsClinical depression was present in approximately 10%, any somatic disorder in 20.21% (9.90% both), and a history of any mental disorder was present in 42.75%. The healthy individuals (46.94% of the study sample) were experiencing distress (8.6%) and subthreshold mental symptoms (attenuated psychotic, schizotypal distrust, emotional lability, conformity, and interpersonal and social functioning). Attenuated psychotic symptoms are present in almost 10%, and the conversion rate to any kind of psychosis was probably 0.5% per year until the age of 40, with one-third of these persons eventually converting. Beyond the age of 40, no conversion to psychosis seems to occur. All aspects of symptoms correlated weakly but significantly with aspects of functional impairment.

conclusionsThe results of the current study are in accord with the literature and suggest that a significant number of persons in the general population experience attenuated psychiatric symptoms and mild functional impairment without ever manifesting an overt mental disorder. There is a need for further research on this matter to confirm these findings and to explore their implications both for mental and somatic health and the provision of health care.

Indexed as

Mental DisordersAdolescentAdultAgedCross-Sectional StudiesDepressionFemaleGreeceHumansMaleMiddle AgedPsychotic DisordersYoung Adultattenuated psychosisgeneral populationsubthreshold symptoms

Identifiers

PMID39969046
PMCPMC13064761

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.