Evidence map›Paper›PMID 39968975›Full record

ArticleArquivos brasileiros de cardiologia2024

Impact of Intraventricular Blocks on Cardiac Cycle Dynamics: An Echocardiographic and Vectorcardiographic Analysis.

Carlos Eduardo Duarte, Katia Regina Silva, Luciene Dias de Jesus, Henry Abensur, Roberto Costa

Abstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carlos Eduardo DuarteInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0001-6671-0820
Katia Regina SilvaInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0002-5723-8285
Luciene Dias de JesusBeneficência Portuguesa de São Paulo, São Paulo, SP - Brasil.
Henry AbensurBeneficência Portuguesa de São Paulo, São Paulo, SP - Brasil.
Roberto CostaInstituto do Coração do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP - Brasil.ORCID 0000-0001-6104-9113

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft bundle branch block (LBBB) causes delays that alter the mechanics of the ventricular cycle. The effect of other intraventricular blocks (IVB) remains little explored.

objectivesTo study the phases of the cardiac cycle (CC) and ventricular synchrony in different ventricular activation patterns.

methodsCross-sectional study with 328 consecutive individuals without structural heart disease, normal electrocardiogram or IVB, conducted in the period between August/2020 and January/2022. Echocardiogram and Vectorcardiogram were performed simultaneously to analyze the electromechanics of the CC. A one-way Analysis of Variance (ANOVA) with Bonferroni's multiple comparison test was used, with a significance level of 5%.

resultsThe age of the participants was 64.8±15.3 years, with 57.9% male and an ejection fraction of 67.0±6.8%. The electrocardiogram was normal for 32.3%, 18.6% had right bundle branch block (RBBB), 17.7% had left anterior fascicular block (LAFB), 15.6% had RBBB+LAFB, and 15.9% had LBBB. The echocardiogram showed an increased left ventricular pre-ejection by 18.7% (p<0.001) and 56.8% (p<0.001) in RBBB+LAFB and LBBB, respectively. There was a post-systolic myocardial contraction in all types of IVB and ventricular dyssynchrony in LBBB. Using the vectorcardiogram, initial activation of the R wave was increased by 17.4% in LAFB (p<0.001), 43.5% in RBBB+LAFB (p<0.001) and 47.4% in LBBB (p<0.001) and delayed final activation by 69.4% in LBBB (p<0.001), 73.6% in RBBB+LAFB (p<0.001) and 95.3% in RBBB (p<0.001).

conclusionAll IVBs modified the CC; however, only LBBB and RBBB+LAFB significantly changed the left ventricular cycle, thereby evidencing the greater complexity of these disorders.

Indexed as

Bundle-Branch BlockEchocardiographyHeart BlockHeart VentriclesVectorcardiographyAgedCross-Sectional StudiesElectrocardiographyFemaleHumansMaleMiddle AgedReference ValuesVentricular Function, Left

Identifiers

PMID39968975
PMCPMC11634305

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.