Evidence map›Paper›PMID 39968791›Full record

Observational studyJournal of the American Heart Association2025

Association of Racial Residential Segregation and Survival After Out-of-Hospital Cardiac Arrest in the United States.

Ethan E Abbott, David G Buckler, Aditya C Shekhar, Elizabeth Landry, Benjamin S Abella, Lynne D Richardson, Alexis M Zebrowski, and the CARES Surveillance Group

Abstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ethan E AbbottDepartment of Emergency Medicine Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-3295-7996
David G BucklerDepartment of Emergency Medicine Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-6018-8282
Aditya C ShekharIcahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-2710-2854
Elizabeth LandryFrank H. Netter MD School of Medicine/Quinnipiac University North Haven CT.
Benjamin S AbellaDepartment of Emergency Medicine Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0003-2521-0891
Lynne D RichardsonDepartment of Emergency Medicine Icahn School of Medicine at Mount Sinai New York NY.ORCID 0000-0002-5425-1601
Alexis M ZebrowskiDepartment of Emergency Medicine Icahn School of Medicine at Mount Sinai New York NY.
and the CARES Surveillance GroupEmory University Atlanta GA.

Funding

Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
Addressing Disparities in Out-of-Hospital Cardiac Arrest: Utilization of Health-Related Social Needs and Predictive Analytics to Improve Clinical OutcomesK08HL169980 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ethan Abbott · 2024 to 2026
$502k
NCATS NIH HHS UL1 TR004419NHLBI NIH HHS K08 HL169980NIH HHS S10 OD026880NIH HHS S10 OD030463
6 · The paper itself

Abstract

backgroundSocial determinants of health such as residential segregation have been identified as drivers of disparities in health outcomes; however, this has been understudied for out-of-hospital cardiac arrest (OHCA). We sought to examine whether there were differences in survival to discharge and survival with good neurological outcome, as well as likelihood of bystander cardiopulmonary resuscitation, using validated measures of racial, ethnic, and economic segregation.

methodsWe conducted a retrospective observational study using data from the Cardiac Arrest Registry to Enhance Survival data set. The primary predictor for this study was the Index of Concentration at the Extremes. The primary outcomes were survival to discharge and survival with good neurological status.

resultsDuring the study period, 626 264 had an out-of-hospital cardiac arrest, and patients had a mean age of 62 years (SD 17.2 years). In multivariable models, we observed an increased likelihood of survival to discharge and survival with good neurological outcome for those patients residing in more highly segregated predominately White population and higher-income census tracts as compared with more highly segregated and lower-income Black and Hispanic/Latinx population census tracts. We found that the magnitude of this disparity was 24% for the outcome of survival to discharge as compared with reference (relative risk,1.24 [95% CI, 1.20-1.28]).

conclusionsThis research suggests that areas impacted by residential and economic segregation are important targets for both public policy interventions as well as addressing disparities in care across the chain of survival for out-of-hospital cardiac arrest.

Indexed as

Healthcare DisparitiesOut-of-Hospital Cardiac ArrestSocial SegregationAgedBlack or African AmericanCardiopulmonary ResuscitationFemaleHealth Status DisparitiesHumansMaleMiddle AgedRegistriesResidential SegregationRetrospective StudiesRisk FactorsSocial Determinants of Healthout‐of‐hospital cardiac arrestracial residential segregationsurvival outcomes

Identifiers

PMID39968791
PMCPMC12132634

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.