Evidence map›Paper›PMID 39968781›Full record

ArticleJournal of the American Heart Association2025

Associations of a Composite Stress Measurement Tool With Cardiovascular Risk Factors and Outcomes: Findings From the Dallas Heart Study.

Ijeoma Eleazu, Colby Ayers, Ann Marie Navar, Karim Salhadar, Michelle Albert, Mercedes Carnethon, E Sherwood Brown, Lucy Ogbu Nwobodo, Spencer Carter, Courtney Bess and 2 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Ijeoma EleazuUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0002-1838-9849
Colby AyersUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0003-2060-2263
Ann Marie NavarUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0002-6197-9860
Karim SalhadarUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0002-9178-3578
Michelle AlbertUniversity of California, San Francisco Medical Center San Francisco CA USA.
Mercedes CarnethonNorthwestern University Chicago IL USA.ORCID 0000-0001-7035-0848
E Sherwood BrownUniversity of Texas Southwestern Medical Center Dallas TX USA.
Lucy Ogbu NwobodoUniversity of California, San Francisco Medical Center San Francisco CA USA.
Spencer CarterUniversity of Texas Southwestern Medical Center Dallas TX USA.
Courtney BessUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0001-9173-4250
Tiffany M Powell-WileySocial Determinants of Obesity and Cardiovascular Risk Laboratory, Cardiovascular Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute National Institutes of Health Bethesda MD USA.ORCID 0000-0001-9488-4131
James A de LemosUniversity of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0003-2211-7261

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeffrey M Zigman · 2022 to 2026
$7.4M
Training in Cardiovascular ResearchT32HL125247 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI JOSEPH A HILL · 2015 to 2026
$4.3M
NCATS NIH HHS UL1 TR001105NHLBI NIH HHS T32 HL125247NIDDK NIH HHS P30 DK127984
6 · The paper itself

Abstract

backgroundMost data linking chronic stress with cardiovascular disease (CVD) risk factors and outcomes have focused on single-domain stress measurements. We evaluated the association between a novel composite measure of chronic perceived stress and CVD risk factors and outcomes in a diverse population. METHODS AND

resultsIndividual chronic stress subcomponents (generalized stress, psychosocial, financial, and neighborhood stress) were standardized and integrated to create a novel composite stress score (CSS). Participants from the DHS (Dallas Heart Study) phase 2 (2007-2009) visit without prevalent CVD who completed chronic stress questionnaires were included (n=2685). Associations between CSS and demographics, cardiac risk factors, and health behaviors were assessed in multivariable analyses. Cox proportional hazards models adjusting for traditional risk factors were used to determine associations of the CSS with adjudicated atherosclerotic CVD and global CVD (atherosclerotic CVD, heart failure, and atrial fibrillation) outcomes. CSS was higher among participants who were younger, women, and Black or Hispanic individuals, with lower income and educational attainment (

conclusionsComposite measures of chronic stress are higher in vulnerable populations and may help identify individuals at risk for CVD who may benefit from enhanced prevention strategies.

Indexed as

Cardiovascular DiseasesStress, PsychologicalAdultAgedFemaleHeart Disease Risk FactorsHumansMaleMiddle AgedRisk AssessmentRisk FactorsSurveys and QuestionnairesTexascardiovascular diseasechronic stressrisk factors

Identifiers

PMID39968781
PMCPMC12132766

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.