Evidence map›Paper›PMID 39968756›Full record

ReviewDisease models & mechanisms2025

Translational lessons from the balanced immune system in bats.

Wei Lun Ng, Lin-Fa Wang

Abstract readReview
In one paragraph

Review in Disease models & mechanisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Wei Lun NgProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.ORCID 0000-0003-1533-9325
Lin-Fa WangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore 169857, Singapore.ORCID 0000-0003-2752-0535

Funding

Ministry of Education - Singapore MOE2019-T2-2-130National Medical Research Council MOH OFIRG19nov-0006National Research Foundation Singapore NRF-CRP10-2012-05
6 · The paper itself

Abstract

Bats are a natural reservoir for a wide variety of notorious viruses that are deadly to humans and other mammals but cause no or minimal clinical damage in bats. The co-evolution of bats and viruses for more than sixty million years has established unique and balanced immune defenses within bats against a number of viruses. With the COVID-19 pandemic, bats have gained greater attention as a likely reservoir of the SARS-CoV-2 ancestor virus. The coupling of omics technology and bat research opens an exciting new field to understand and translate discoveries from bats to humans, in the context of infectious disease and beyond. Here, we focus on the mechanism of immunity balance in bats, the application of omics and how this might lead to improvement of human health.

Indexed as

ChiropteraImmune SystemTranslational Research, BiomedicalAnimalsCOVID-19HumansSARS-CoV-2Bat biologyBat immunologyEmerging infectious diseases

Identifiers

PMID39968756
PMCPMC11876839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.