Evidence map›Paper›PMID 39968736›Full record

ArticleJournal of veterinary internal medicine

Antimicrobial Administration Practices in Hospitalized Periparturient Goats: A Multicenter Study.

Daniela Luethy, Catalina Cabrera, Lisette M Coll-Roman, Ashley R VanderBroek, Sarah M Depenbrock, Anje G Bauck, Audrey A Kelleman, Jenna W Stockler, Clare Scully, Caitlin Wiley and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Daniela LuethyClinical Studies-New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.ORCID https://orcid.org/0000-0003-1693-2147
Catalina CabreraDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.ORCID https://orcid.org/0000-0003-3802-406X
Lisette M Coll-RomanDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Ashley R VanderBroekDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, USA.
Sarah M DepenbrockDepartment of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, UC Davis, Davis, California, USA.ORCID https://orcid.org/0000-0002-3481-776X
Anje G BauckDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Audrey A KellemanDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.
Jenna W StocklerDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, Alabama, USA.ORCID https://orcid.org/0000-0002-6502-7445
Clare ScullyDepartment of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana, USA.
Caitlin WileyVeterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Evelyn E MackayDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
Michelle AbrahamClinical Studies-New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.
Laurence LeducClinical Studies-New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.ORCID https://orcid.org/0009-0005-6676-7137
Charlene V NollDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA.
Marie-Eve FecteauClinical Studies-New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.
Laurel E ReddingClinical Studies-New Bolton Center, University of Pennsylvania, Kennett Square, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-3414-1202

Funding

Impact of pet contact on antimicrobial-associated dysbiosis and Clostridioides difficile infectionK23AI163351 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Laurel Elizabeth Redding · 2022 to 2026
$896k
National Institutes of Health/National Institute of Allergy and Infectious Diseases for Laurel E. Redding K23AI163351NIAID NIH HHS K23 AI163351
6 · The paper itself

Abstract

backgroundUnderstanding antimicrobial use practices in goats is essential to ensuring appropriate antimicrobial stewardship.

objectiveTo describe antimicrobial prescriptions in periparturient does admitted to veterinary teaching hospitals and to determine if any factors were associated with the administration of antimicrobials in general or ceftiofur in particular. ANIMALS: One hundred ninety-eight periparturient does presented to nine university veterinary hospitals from October 2021 to June 2022.

methodsA multicenter cross-sectional study in a prospective design. Data were collected from questionnaire completed by admitting clinician.

resultsOut of 198 periparturient does included in the study, 153 (77%) received antimicrobials during hospitalization. Commonly administered antimicrobials included oxytetracycline (n = 44, 29%), ceftiofur sodium (n = 43, 28%), ceftiofur crystalline free acid (CCFA; n = 27, 18%), potassium penicillin G (n = 15, 10%), procaine penicillin G (n = 14, 9%), florfenicol (n = 14, 9%), tulathromycin (n = 9, 6%), ampicillin trihydrate (n = 4, 3%), and ampicillin sodium (n = 1, 1%). Cesarean section was associated with antimicrobial administration in general (OR = 5.89; 95% CI = 2.49-13.98, p < 0.01) and with ceftiofur administration (OR = 2.54, 95% CI = 1.25-5.17; p = 0.008). Significant variability in ceftiofur administration by hospital was observed (p < 0.001). CONCLUSIONS AND CLINICAL IMPORTANCE: Marked heterogeneity was observed in the antimicrobial administration practices in periparturient goats between nine US veterinary teaching hospitals.

Indexed as

Anti-Bacterial AgentsGoat DiseasesAnimalsCephalosporinsCross-Sectional StudiesFemaleGoatsHospitalizationHospitals, AnimalPregnancyProspective StudiesAnti-Bacterial AgentsceftiofurCephalosporinsantibiotic choicesantimicrobialsantimicrobial stewardshipcaprineceftiofurpharmacology

Identifiers

PMID39968736
PMCPMC11836665

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.