Evidence map›Paper›PMID 39968731›Full record

ArticleJournal of veterinary internal medicine

Association of Extreme Brachycephaly With Persistent Fontanelles in Adult Chihuahuas.

Elina Rautala, Tarja S Jokinen, Junnu Leikola, Mirja Ruohoniemi, Clare Rusbridge, Jouni J T Junnila, Anna-Mariam Kiviranta

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elina RautalaDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-1769-7559
Tarja S JokinenDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Junnu LeikolaCleft Palate and Craniofacial Centre, Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Mirja RuohoniemiDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.
Clare RusbridgeSchool of Veterinary Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.ORCID https://orcid.org/0000-0002-3366-2110
Jouni J T JunnilaEstiMates Oy, Espoo, Finland.
Anna-Mariam KivirantaDepartment of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.ORCID https://orcid.org/0000-0002-9542-7247

Funding

Agria/Svenska Kennelklubben Forskningsfond N2018-0024Eläinlääketieteen Tutkimuksen TukisäätiöFinnish Kennel Club's research fund
6 · The paper itself

Abstract

backgroundAlthough persistent fontanelles (PFs) are common in adult Chihuahuas, their association with cranial morphology remains unknown.

objectivesTo identify whether cranial morphology is associated with PFs in Chihuahuas and if bodyweight is associated with cranial morphology in this breed. ANIMALS: Fifty client-owned Chihuahuas.

methodsIn this retrospective cross-sectional study using computed tomography images, we measured two different cranial base lengths (1 and 2), cranial length, height, and width, and two craniofacial angles. We calculated the ratios of cranial height to cranial base lengths 1 and 2, cranial height to length, cranial height to width, and cranial width to length (cranial index [CrI]). We evaluated if total PF area and number of cranial sutures affected by PFs were associated with craniometric measurements and their ratios and craniofacial angles. Additionally, we evaluated if the craniometric ratios were associated with bodyweight.

resultsTotal PF area was larger and number of cranial sutures affected by PFs higher in dogs with higher cranial height to cranial base length ratios 1 (estimate, [95% confidence interval], p: 2.295, [1.204-4.377], p = 0.01 and 1.720, [1.212-2.442], p = 0.002, respectively) and 2 (1.203, [1.069-1.354], p = 0.003 and 1.087, [1.011-1.169], p = 0.02, respectively) and CrI (1.225, [1.079-1.391], p = 0.002, and 1.134, [1.057-1.215], p < 0.001, respectively). Higher CrI was associated with lower bodyweight (-2.600, [-4.102 to -1.098], p = 0.001). CONCLUSION AND CLINICAL IMPORTANCE: Our results suggest that in Chihuahuas, lower bodyweight is associated with more extreme brachycephaly and extreme brachycephaly is associated with PFs.

Indexed as

Cranial FontanellesCraniosynostosesDog DiseasesAnimalsBody WeightCranial SuturesCross-Sectional StudiesDogsFemaleMaleRetrospective StudiesTomography, X-Ray Computedcomputed tomographycranial basecranial indexcraniometric measurement

Identifiers

PMID39968731
PMCPMC11836668

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.