Evidence map›Paper›PMID 39968713›Full record

ArticleJournal of cosmetic dermatology2025

Skincare Benefits of a Postbiotic Ferment Produced Through Djon Djon Mushroom Fermentation by Saccharomyces.

Chunhong Pu, Doudou Shi, Michael Ingrassia, Harvey Gedeon, Tye Chu, Jiachan Zhang, Changtao Wang

Abstract read
In one paragraph

Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chunhong PuBeijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University, Beijing, P. R. China.ORCID https://orcid.org/0009-0006-4359-8753
Doudou ShiBeishang Jiamei (Beijing) Technology Co. Ltd., Beijing, P. R. China.
Michael IngrassiaDermegen Inc., Hauppauge, New York, USA.
Harvey GedeonLaboratoire de Furcy LLC, El Portal, Florida, USA.
Tye ChuDermegen Inc., Hauppauge, New York, USA.
Jiachan ZhangBeijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University, Beijing, P. R. China.
Changtao WangBeijing Key Lab of Plant Resource Research and Development, Beijing Technology and Business University, Beijing, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDjon Djon is a particularly special black mushroom indigenous to Haiti that has a long history in both their cuisine and in traditional medicine. Centuries of folkloric utilization of theses "medicinal" botanicals tend to indicate the presence of a potentially efficacious western medicine entity.

objectivesWith the advantages afforded by both traditional medicines and fermentation, we endeavored to investigate if fermentation of Djon Djon mushrooms can provide skin care benefits.

methodsIn this study, active Djon Djon fermentation broth (DDF) was obtained using Saccharomyces, and anti-inflammatory efficacy was assessed in cultured systems using human keratinocytes and fibroblasts, exposed to either UVB or H

resultsCharacterization of the DDF displayed a high number of polysaccharides and peptides present following fermentation, that function to scavenge intracellular ROS, decrease MDA content, while increasing the levels of CAT, COL-I, and HA in HSF induced by H

conclusionDDF can alleviate oxidative stress damage caused by hydrogen peroxide and photodamage caused by UVB, and the mechanism by which DDF protects skin cells is revealed, displaying the potential benefits of fermented DjonDjon in skincare.

Indexed as

Anti-Inflammatory AgentsSaccharomycesSkin CareFermentationFibroblastsHaCaT CellsHumansHydrogen PeroxideKeratinocytesSkinUltraviolet RaysAnti-Inflammatory AgentsHydrogen PeroxideDjon Djonfermentationinflammationoxidative stressphotodamageRNA‐sequencing

Identifiers

PMID39968713
PMCPMC11836922

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.