Evidence map›Paper›PMID 39968503›Full record

ReviewAnalytical science advances2025

Cost-Effective Nanosensor Solutions for Ultra-Sensitive Detection of Metronidazole.

Ahmad Mobed, Mohammad Darvishi, Vahid Alivirdiloo, Sara Ebrahimi, Mobasher Hajiabbasi, Farhood Ghazi, Hamidreza Hassanzadeh Khanmiri

Abstract readReview
In one paragraph

Review in Analytical science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmad MobedSocial Determinants of Health Research Center Tabriz University of Medical Sciences Tabriz Iran.ORCID https://orcid.org/0000-0001-8939-3688
Mohammad DarvishiInfectious Disease, School of Aerospace and Subaquatic Medicine, Infectious Diseases & Tropical Medicine Research Center (IDTMC) AJA University of Medical Sciences Tehran Iran.
Vahid AlivirdilooMedical Doctor Department of Physiology and Pharmacology Mazandaran University of Medical Sciences Ramsar Iran.
Sara EbrahimiFaculty of Medicine Tabriz University of Medical Sciences Tabriz Iran.
Mobasher HajiabbasiMedical Doctor Department of Physiology and Pharmacology Mazandaran University of Medical Sciences Ramsar Iran.
Farhood GhaziFaculty of Medicine Tabriz University of Medical Sciences Tabriz Iran.
Hamidreza Hassanzadeh KhanmiriDepartment of Basic Sciences, Maragheh Branch Islamic Azad University Maragheh Iran.ORCID https://orcid.org/0000-0002-2241-8059

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic-associated colitis. However, prolonged and excessive use of MNZ can lead to serious side effects, such as peripheral neuropathies, toxicity, and optic neuropathy. Therefore, the accurate detection and removal of MNZ present significant technical challenges. This manuscript introduces novel approaches for the development and integration of precise and cost-effective sensors specifically designed for the accurate measurement of MNZ levels. We explore cutting-edge nanotechnology strategies for detecting MNZ, with a particular focus on innovative nanobiosensors, including photodynamic-based biosensors, acousto dynamic sensors, and electrochemical biosensors. Additionally, we delve into the unique challenges and opportunities associated with multiphysics biometric biosensors and related nanotechnologies in the detection of MNZ. This review not only provides insights and scientific evidence regarding the application of nanobiosensors for the accurate measurement of MNZ but also highlights recent advancements in sensor technology that represent a significant leap forward in this field. By emphasizing these novel contributions, we aim to pave the way for future research and development in this critical area. Ultimately, our findings underscore the importance of reliable detection methods in mitigating the risks associated with MNZ use and improving patient safety.

Indexed as

antibioticbiosensorselectrochemicalmetronidazole

Identifiers

PMID39968503
PMCPMC11833170

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.