Evidence map›Paper›PMID 39968347›Full record

ReviewBioinorganic chemistry and applications2025

A Comprehensive Review of the Biological Activities of Medicinal Metal Complexes Synthesized From Quinoline Scaffolds.

Sabikeh G Azimi, Neda Shakour, Ghodsieh Bagherzade, Mohammad Reza Saberi, Hosseinali Azimi, Mehdi Moosavi F

Abstract readReview
In one paragraph

Review in Bioinorganic chemistry and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sabikeh G AzimiDepartment of Chemistry, Faculty of Sciences, University of Birjand, Birjand 97175-615, Iran.ORCID https://orcid.org/0000-0002-3204-2075
Neda ShakourDepartment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0002-9874-1397
Ghodsieh BagherzadeDepartment of Chemistry, Faculty of Sciences, University of Birjand, Birjand 97175-615, Iran.ORCID https://orcid.org/0000-0003-2931-8146
Mohammad Reza SaberiDepartment of Medicinal Chemistry, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.ORCID https://orcid.org/0000-0003-3929-6657
Hosseinali AzimiDepartment of Research and Development, Parthkimia Pharmaceutical Co., Gorgan, Iran.ORCID https://orcid.org/0000-0002-3412-5173
Mehdi Moosavi FDepartment of Organic Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran.ORCID https://orcid.org/0009-0005-9118-8495

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The compelling attributes of quinoline scaffolds in medicinal compounds have garnered considerable attention from researchers, due to their notable biological efficacy, biocompatibility, and distinctive photophysical properties. Quinoline complexes, in particular, have emerged as significant entities, demonstrating a wide array of medicinal properties, including antibacterial, antifungal, antiviral, anticancer, anthelmintic, anti-HIV, antioxidant, antituberculosis, and antimalarial activities. In addition, they showed promise in photodynamic and neurological studies, along with strong DNA-binding capabilities. In recent years (2010-2023), substantial progress has been made in understanding quinoline complexes. Key aspects such as the lipophilicity, of metal complexes, enzymatic drug degradation factors influencing inhibition, drug performance, disruption of target cell growth, and their impact on DNA have been thoroughly investigated. Researchers have employed advanced methodologies including fluorescent imaging, determination of MIC and IC

Indexed as

biological activityDNA bindingdrug performancein silico studiesmedicinal metal complexesquinoline scaffold

Identifiers

PMID39968347
PMCPMC11835480

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.