Evidence map›Paper›PMID 39968345›Full record

ArticleDialogues in health2025

Beyond antiretroviral treatment: Health-related quality of life of patients receiving antiretroviral treatment at a tertiary hospital in South Africa.

Govinda Rajan Gudala, Neelaveni Padayachee, Rajesh Vikram Vagiri

Abstract read
In one paragraph

Article in Dialogues in health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Restoring well-being: quality of life improvements following dolutegravir-based therapy after antiretroviral failure.The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Govinda Rajan GudalaDepartment of Pharmacy and Pharmacology, School of Therapeutic Sciences, University of the Witwatersrand, Postal Details: 8, Minerva Avenue, Cresta, Randburg, Johannesburg 2194, South Africa.
Neelaveni PadayacheeDepartment of Pharmacy and Pharmacology, School of Therapeutic Sciences, University of the Witwatersrand, Postal Details: 8, Minerva Avenue, Cresta, Randburg, Johannesburg 2194, South Africa.
Rajesh Vikram VagiriDepartment of Pharmacy, Faculty of Health Sciences, University of Limpopo, South Africa.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antiretroviral therapy (ART) has significantly transformed the management of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS), positively impacting the health-related quality of life (HRQoL) and life expectancy of people living with HIV and AIDS (PLWHA). HRQoL is a critical consideration for HIV and AIDS patients as it reflects their overall well-being and treatment outcomes. This study aimed to investigate the HRQoL of PLWHA receiving an ART regimen containing tenofovir, lamivudine, and dolutegravir at a tertiary hospital in Johannesburg, South Africa. This descriptive, quantitative, cross-sectional study included 103 patients who consented in writing to participate. Data was collected using WHOQOL HIV-BREF, socio-demographic, health characteristics, and adherence questionnaires. Participants who reported 'excellent' and 'very good' on the descriptive rating scale were considered to have optimal adherence (≥95 %). This study's statistical significance was set at

Indexed as

AdherenceHealth-related quality of lifePeople living with HIV and AIDSTreatment outcomesWell-being

Identifiers

PMID39968345
PMCPMC11833624

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.