Evidence map›Paper›PMID 39968301›Full record

Observational studyFrontiers in endocrinology2025

COVID-19 in discharged patients with diabetes and chronic kidney disease: one-year follow-up and evaluation.

Enrong Ran, Yutong Zou, Chuanyi Zhao, Kai Liu, Jiamin Yuan, Wenjie Yang, Lijun Zhao, Qing Yang, Jia Yang, Xuegui Ju and 5 more

Abstract readObservational Study
In one paragraph

Observational study in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Enrong RanDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yutong ZouDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Chuanyi ZhaoDepartment of Clinical Research Management, West China Hospital of Sichuan University, Chengdu, China.
Kai LiuDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jiamin YuanDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Wenjie YangDivision of Project Design and Statistics, West China Hospital of Sichuan University, Chengdu, China.
Lijun ZhaoDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Qing YangDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jia YangDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xuegui JuDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Linli CaiDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yanlin LangDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Xingyuan LiDepartment of Clinical Research Management, West China Hospital of Sichuan University, Chengdu, China.
Ke LiuDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Fang LiuDepartment of Nephrology, West China Hospital, Sichuan University; Laboratory of Diabetic Kidney Disease, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the all-cause mortality rate and renal outcomes in patients with diabetes and chronic kidney disease (CKD) following hospital discharge for COVID-19. Methods: This single-center prospective observational study included 187 discharged COVID-19 patients with diabetes and CKD, admitted between December 2022 and January 2023 at West China Hospital, Sichuan University. Cox regression analysis was used to assess mortality risk, and logistic regression was applied to identify risk factors for rapid CKD progression after discharge. Results: During the one-year follow-up, the all-cause mortality rate was 26.7%, with a COVID-19-related acute kidney injury (AKI) incidence of 35.3%, and 35.8% of patients experienced rapid CKD progression after discharge. Cox proportional hazards regression indicated that sepsis and mechanical ventilation were major risk factors for post-discharge all-cause mortality. Logistic regression identified baseline eGFR < 60 mL/min/1.73 m² as an independent risk factor for rapid CKD progression. Conclusions: During the one-year follow-up period, we observed that patients with diabetes and CKD exhibited higher all-cause mortality and experienced rapid deterioration of kidney function after acute infection with COVID-19. This underscores the importance of ongoing longitudinal follow-up to more accurately track the long-term health effects of COVID-19 on patients with diabetes and CKD.

Indexed as

COVID-19Diabetes MellitusRenal Insufficiency, ChronicAcute Kidney InjuryAdultAgedChinaDisease ProgressionFemaleFollow-Up StudiesGlomerular Filtration RateHumansMaleMiddle AgedPatient DischargeProspective Studiesacute kidney injurychronic kidney diseaseCOVID-19diabetesmortality

Identifiers

PMID39968301
PMCPMC11832373

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.