Evidence map›Paper›PMID 39968169›Full record

ArticleBeilstein journal of nanotechnology2025

Probing the potential of rare earth elements in the development of new anticancer drugs: single molecule studies.

Josiane A D Batista, Rayane M de Oliveira, Carlos H M Lima, Milton L Lana Júnior, Virgílio C Dos Anjos, Maria J V Bell, Márcio S Rocha

Abstract read
In one paragraph

Article in Beilstein journal of nanotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Josiane A D BatistaDepartamento de Física, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Rayane M de OliveiraDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0001-5992-5994
Carlos H M LimaDepartamento de Ciências Naturais, Universidade Federal do Acre, Rio Branco, Acre, Brazil.ORCID https://orcid.org/0000-0002-6690-5668
Milton L Lana JúniorDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0006-7943-8524
Virgílio C Dos AnjosDepartamento de Física, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0003-2279-0384
Maria J V BellDepartamento de Física, Universidade Federal de Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Márcio S RochaDepartamento de Física, Universidade Federal de Viçosa, Viçosa, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0003-0323-3718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We use optical tweezers and atomic force microscopy to investigate the potential of rare earth elements to be used as anticancer agents in the development of new chemotherapeutic drugs by characterizing the binding of three rare earths (ytterbium, neodymium, and erbium) to double-stranded DNA, which is one of the main targets for these drugs inside cells. The three elements presented a significant interaction with the biopolymer in buffers of physiological relevance, typically binding with very high equilibrium association constants (10

Indexed as

DNAoptical tweezersrare earth elementssingle molecule force spectroscopy

Identifiers

PMID39968169
PMCPMC11833172

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.