Evidence map›Paper›PMID 39967969›Full record

ArticleInternational journal of ophthalmology2025

Visual electrophysiological assessment of children with poor response to treatment for functional amblyopia.

Dong-Qing Yuan, Wei-Wei Zhang, Liu-Wei Gu, Qing-Huai Liu

Abstract read
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Article in International journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Dong-Qing YuanDepartment of Ophthalmology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Women and Children Health Hospital, Nanjing 210029, Jiangsu Province, China.
Wei-Wei ZhangDepartment of Ophthalmology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Women and Children Health Hospital, Nanjing 210029, Jiangsu Province, China.
Liu-Wei GuDepartment of Ophthalmology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Women and Children Health Hospital, Nanjing 210029, Jiangsu Province, China.
Qing-Huai LiuDepartment of Ophthalmology, Jiangsu Province Hospital, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Women and Children Health Hospital, Nanjing 210029, Jiangsu Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the visual electrophysiological outcomes in children with functional amblyopia who exhibited poor response to conventional treatment.

methodsTwenty-one children with functional amblyopia, aged 5.7±2.1y (range: 4-10y), underwent comprehensive ophthalmic and refractive evaluations. Spectral domain-optical coherence tomography (SD-OCT) and multifocal electroretinography (mfERG) were conducted to analyze the macular retinal thickness and the first-order response P1 ring of the mfERG in the amblyopic eye (AE) compared to the fellow good eye (GE).

resultsInitially, visual acuity in the AE ranged from 20/800 to 20/40, while the GE exhibited a range of 20/25 to 20/20 (

conclusionIn the management of functional amblyopia, a thorough assessment of amblyopic eye examinations is crucial. Approximately 20% of amblyopic eyes may not achieve significant improvement in visual acuity, despite the absence of detectable organic retinal abnormalities. mfERG may reveal underlying abnormalities. Integrating mfERG into initial assessments or treatment follow-ups can aid in identifying potential hidden retinal defects and predicting the prognosis of the amblyopic eye.

Indexed as

functional amblyopiamultifocal electroretinographyoptical coherence tomographypoor responseretinal defects

Identifiers

PMID39967969
PMCPMC11754019

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