Evidence map›Paper›PMID 39967886›Full record

ReviewRSC advances2025

Metal nanoparticles in neuroinflammation: impact on microglial dynamics and CNS function.

Masood Alaei, Khadijeh Koushki, Kimia Taebi, Mahdieh Yousefi Taba, Samaneh Keshavarz Hedayati, Sanaz Keshavarz Shahbaz

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masood AlaeiStudent Research Committee, Qazvin University of Medical Sciences Qazvin Iran.
Khadijeh KoushkiDepartment of Neurosurgery, University of Texas Houston Health Science Center (UTHealth) Houston TX USA.
Kimia TaebiStudent Research Committee, Qazvin University of Medical Sciences Qazvin Iran.
Mahdieh Yousefi TabaDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mashhad University of Medical Sciences Mashhad Iran.
Samaneh Keshavarz HedayatiDepartment of Pharmacology, Faculty of Medicine, Qazvin University of Medical Science Qazvin Iran.
Sanaz Keshavarz ShahbazCellular and Molecular Research Center, Research Institute for Prevention of Non-Communicable Disease, Qazvin University of Medical Sciences Qazvin 34197-59811 Iran.ORCID https://orcid.org/0000-0001-7333-5969

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microglia, the primary immune cells of the central nervous system (CNS), are crucial in maintaining brain homeostasis and responding to pathological changes. While they play protective roles, their activation can lead to neuroinflammation and the progression of neurodegenerative diseases. Metal nanoparticles (NPs), due to their unique ability to cross the blood-brain barrier (BBB), have emerged as promising agents for drug delivery to the CNS. In this way, we aim to review the dual role of metal-containing NPs, gold (AuNPs), silver (AgNPs), iron oxide (IONPs), zinc oxide (ZnONPs), cobalt (CoNPs), titanium dioxide (TiO

Identifiers

PMID39967886
PMCPMC11833603

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.