Evidence map›Paper›PMID 39967847›Full record

ArticleAJOG global reports2025

Variations in emergency care for severe pre-eclampsia in Uganda: a national evaluation study.

Annettee Nakimuli, Jackline Akello, Musa Sekikubo, Sarah Nakubulwa, Moses Adroma, Rehema Nabuufu, Emmanuel Obuya, John Paul Bagala, Andrew Twinamatsiko, Hadijah Nakatudde and 10 more

Abstract read
In one paragraph

Article in AJOG global reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Annettee NakimuliDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University, Kampala, Uganda (Nakimuli, Akello, Sekikubo, Nakubulwa, Adroma).
Jackline AkelloDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University, Kampala, Uganda (Nakimuli, Akello, Sekikubo, Nakubulwa, Adroma).
Musa SekikuboDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University, Kampala, Uganda (Nakimuli, Akello, Sekikubo, Nakubulwa, Adroma).
Sarah NakubulwaDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University, Kampala, Uganda (Nakimuli, Akello, Sekikubo, Nakubulwa, Adroma).
Moses AdromaDepartment of Obstetrics and Gynaecology, School of Medicine, Makerere University, Kampala, Uganda (Nakimuli, Akello, Sekikubo, Nakubulwa, Adroma).
Rehema NabuufuDepartment of Obstetrics and Gynaecology, Kawempe National Referral Hospital, Kampala, Uganda (Nakimuli, Akello, Sekikubo, Nakubulwa, Adroma, Nabuufu).
Emmanuel ObuyaSchool of Public Health, Makerere University, Kampala, Uganda (Obuya).
John Paul BagalaMinistry of Health Headquarters, Kampala, Uganda (Bagala, Twinamatsiko, Nakatudde, Mugahi).
Andrew TwinamatsikoMinistry of Health Headquarters, Kampala, Uganda (Bagala, Twinamatsiko, Nakatudde, Mugahi).
Hadijah NakatuddeMinistry of Health Headquarters, Kampala, Uganda (Bagala, Twinamatsiko, Nakatudde, Mugahi).
Patrica PirioUNICEF Uganda Office (Pirio, Latigi), Kampala, Uganda.
Grace LatigiUNICEF Uganda Office (Pirio, Latigi), Kampala, Uganda.
Baifa ArwinyoDepartment of Obstetrics and Gynaecology, Gulu Regional Referral Hospital, Gulu, Uganda (Arwinyo).
Kenneth MugabeDepartment of Obstetrics and Gynaecology, Mbale Regional Referral Hospital, Mbale, Uganda (Mugabe).
Irene ChebetDepartment of Obstetrics and Gynaecology, Soroti Regional Referral Hospital, Soroti, Uganda (Chebet).
Richard MugahiMinistry of Health Headquarters, Kampala, Uganda (Bagala, Twinamatsiko, Nakatudde, Mugahi).
Isabella AitchisonDepartment of Obstetrics and Gynaecology, University of Cambridge, The Rosie Hospital and NIHR Cambridge Biomedical Research Centre, Cambridge, United Kingdom (Aitchison, Patient, Aiken).
Charlotte PatientDepartment of Obstetrics and Gynaecology, University of Cambridge, The Rosie Hospital and NIHR Cambridge Biomedical Research Centre, Cambridge, United Kingdom (Aitchison, Patient, Aiken).
Ashley MoffettDepartment of Pathology and Centre for Trophoblast Research, University of Cambridge, Cambridge, United Kingdom (Moffett).
Catherine E AikenDepartment of Obstetrics and Gynaecology, University of Cambridge, The Rosie Hospital and NIHR Cambridge Biomedical Research Centre, Cambridge, United Kingdom (Aitchison, Patient, Aiken).

Funding

Gates Foundation INV-037049Wellcome Trust
6 · The paper itself

Abstract

Background: Worldwide, 70% of maternal deaths occur in Sub-Saharan Africa. Approximately 10% are attributable to hypertensive disorders of pregnancy, primarily complications of pre-eclampsia. Timely and effective care improves outcomes, but this is not consistently available, particularly in low-resource settings such as Uganda. Objectives: We conducted a national evaluation of the provision of prompt and safe care for women with severe pre-eclampsia across all regions of Uganda. We explored the wider health system-related factors, eg supply availability, facilities, and emergency training drills, that may affect the ability of healthcare facilities to deliver optimal pre-eclampsia care. Study design: A multidisciplinary research team carried out in-person, unannounced visits to maternity facilities across Uganda to assess the quality of care provided. Evaluations of facilities, staff interviews, and case notes reviews were performed. Results: 75 maternity facilities were included from all regions of Uganda. Of these, 25% were unable to provide correct emergency care for severe pre-eclampsia, and 21% were unable to consistently provide delivery or referral for eclamptic seizure within 12 hours. Factors strongly associated with not providing optimal pre-eclampsia care were lack of staff training, lack of readily available clinical protocols, lack of antenatal education, lack of close postnatal monitoring and care that was not always woman-centered. Conclusions: The key barriers associated with delayed or poor quality pre-eclampsia care across Uganda are potentially modifiable with strengthened clinical governance initiatives. Developing context-specific, standardized, national training and educational programmes could be effective in reducing rates of maternal and neonatal morbidity and mortality from pre-eclampsia.

Indexed as

Maternal healthmultidisciplinaryobstetricspre-eclampsiaquality improvementresourcesUganda

Identifiers

PMID39967847
PMCPMC11833625

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.