Evidence map›Paper›PMID 39967832›Full record

ReviewPlant-environment interactions (Hoboken, N.J.)2025

Questions and Consequences of Omics in Genetically Engineered Crop Regulation.

Asa Budnick, Eric Butoto, Nick Loschin, Amanda Mainello-Land, Jill Furgurson, Rebekah Brown, Greg Ferraro, Rex Alirigia, Modesta Abugu, Ruthie Stokes and 2 more

Abstract readReview
In one paragraph

Review in Plant-environment interactions (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Asa BudnickPlant and Microbial Biology North Carolina State University Raleigh North Carolina USA.ORCID https://orcid.org/0009-0004-2987-7567
Eric ButotoGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Nick LoschinGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Amanda Mainello-LandGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Jill FurgursonGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Rebekah BrownGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Greg FerraroGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Rex AlirigiaGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Modesta AbuguGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Ruthie StokesGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Christopher GillespieGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.
Nolan SpeicherGenetic Engineering and Society Center North Carolina State University Raleigh North Carolina USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 2016, a National Academies of Sciences, Engineering, and Medicine advisory committee proposed omics technologies as one possible adequate response to the regulatory challenges posed by gene editing and synthetic biology. This paper presents a set of questions that would need to be answered to integrate omics experiments and data into crop regulatory systems. These questions concern both experimental practice and how omics-experimental and regulatory systems intersect. We anticipate that the chosen answers to these questions will impact the scientific validity, regulatory burden, and usefulness for forecasting risk in nuanced ways. In doing so, we conclude that the integration of omics technologies into regulatory systems poses an array of more-than-technical dilemmas whose management will require cross-sector collaboration and innovative approaches to socio-technical decision-making.

Identifiers

PMID39967832
PMCPMC11832586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.