ArticleFrontiers in cellular and infection microbiology2024
Diverse vaginal microbiota in healthy Japanese women: a combined relative and quantitative analyses.
Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Induction of Human β-Defensin-2 by VaginalOpen forum infectious diseases · 2026Article
- The implications and mechanisms of vaginal microbiota metabolites on cervical cancer progression.Frontiers in cellular and infection microbiology · 2026Review
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Authors and funding
6 authors.
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Abstract
Introduction: This cross-sectional study aimed to characterize the viable vaginal microbiota and identify host factors influencing this microbiota by employing a combination of relative and quantitative analyses. Methods: Twenty-four vaginal fluid samples were collected from healthy adult Japanese women for analysis. Vaginal fluid pH was measured using a portable pH meter. DNA was extracted from the vaginal fluid, and the 16S ribosomal RNA gene sequences in the V3-V4 regions were analyzed to identify bacterial species. Additionally, the vaginal fluid was cultured on four types of selective agar plates. The predominant species in the growing colonies were identified using colony polymerase chain reaction, and the colonies were counted. Results: The vaginal microbiota was classified into four categories based on the characterization of the dominant bacterial population: Conclusions: Our findings indicate that the vaginal microbiome of healthy Japanese women is not only highly diverse but also affected by host factors such as BMI and age.
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