Evidence map›Paper›PMID 39967784›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2025

Cosmetic Therapeutic Keratopigmentation.

Bruno Lovaglio Cançado Trindade, Isadora Brito Coelho, Larissa Lima Magalhães, Letícia Arriel Crepaldi, Frederico Moreira Man Fu, Luiza Machado Ribeiro Da Glória

Abstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. An updated comprehensive review on keratopigmentation.International journal of ophthalmology · 2025
    Review
  2. Ongoing reepithelialization after keratopigmentation.Arquivos brasileiros de oftalmologia · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bruno Lovaglio Cançado TrindadeCornea Department, Instituto de Olhos Ciências Médicas, Belo Horizonte, Brazil.ORCID 0000-0002-6453-2167
Isadora Brito CoelhoCornea Department, Instituto de Olhos Ciências Médicas, Belo Horizonte, Brazil.ORCID 0000-0002-6370-7826
Larissa Lima MagalhãesCornea Department, Instituto de Olhos Ciências Médicas, Belo Horizonte, Brazil.ORCID 0000-0002-0973-1585
Letícia Arriel CrepaldiCornea Department, Instituto de Olhos Ciências Médicas, Belo Horizonte, Brazil.ORCID 0000-0002-8121-5059
Frederico Moreira Man FuFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-7801-0140
Luiza Machado Ribeiro Da GlóriaFaculdade de Ciências Médicas de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0001-7969-8293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To analyze indications safety and potential complications of cosmetic therapeutic corneal keratopigmentation to treat disfiguring aspect of opaque corneas. Methods: Eight eyes of 8 consecutive patients were enrolled in therapeutic corneal keratopigmentation. Surgery was performed using manual technique, and a two-plane corneal dissection was performed. In the deeper pocket, brown pigment was injected to mimic iris color. In the more superficial and smaller pocket, black pigment was used to simulate pupillary opening. Results: Seven out of 8 eyes had significant improvements in cosmesis after surgery. One patient did not have a major improvement due to significant superficial corneal neovascularization. In two eyes, there was pigment fading in the postoperative period, but no additional surgeries were performed. No complications were noted in any of the patients. Conclusion: Therapeutic corneal keratopigmentation can lead to a significant change in ocular appearance and may improve self-esteem and overall life quality. Pigment fading and corneal neovascularization can be a potential problem. Careful patient selection and counseling are important to avoid patients seeking unachievable results.

Indexed as

blind eyecorneal opacitycorneal tattookeratopigmentation

Identifiers

PMID39967784
PMCPMC11832349

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.