Evidence map›Paper›PMID 39966900›Full record

ArticleCell communication and signaling : CCS2025

On the road: extracellular vesicles in intercellular communication.

Silja Wessler, Nicole Meisner-Kober

Abstract readEditorial
In one paragraph

Article in Cell communication and signaling : CCS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  20. Selective DNA encapsulation in extracellular vesicles ofExtracellular vesicles and circulating nucleic acids · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Silja WesslerDepartment of Biosciences and Medical Biology, Center for Tumor Biology and Immunology (CTBI), Paris-Lodron University Salzburg, University of Salzburg, Salzburg, Austria. silja.wessler@plus.ac.at.
Nicole Meisner-KoberDepartment of Biosciences and Medical Biology, Center for Tumor Biology and Immunology (CTBI), Paris-Lodron University Salzburg, University of Salzburg, Salzburg, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cells from organisms across all kingdoms of life continuously release a diverse repertoire of extracellular vesicles (EVs) into their extracellular environment as an elegant strategy for both, cellular homeostasis and communication with other cells. Through different biogenesis routes within the donor cell, nanosized vesicles are generated either from endomembranes or the plasma membrane, and loaded and decorated with macromolecular cargo in a controlled manner through molecular sorting machineries. Since they can affect a recipient cell in the same tissue, distant organs or even other organisms, EVs have been increasingly recognized as essential mediators orchestrating intercellular communication in health and disease. In the last 15 years, research on the fundamental biology of EVs as well as their potential for biomedical applications has been greatly intensified. Time to present new advances on EV biogenesis, their intercellular communication competencies as well as technical and biomedical applications in a special thematic series of Cell Communication and Signaling.

Indexed as

Cell CommunicationExtracellular VesiclesAnimalsHumans

Identifiers

PMID39966900
PMCPMC11837664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.