Evidence map›Paper›PMID 39966899›Full record

ArticleMalaria journal2025

Enhancing the uptake of intermittent preventive treatment for malaria in pregnancy: a scoping review of interventions and gender-informed approaches.

Irene A Kretchy, Deborah Atobrah, David A Adumbire, Samuel Ankamah, Theodosia Adanu, Delali M Badasu, Benjamin K Kwansa

Abstract readScoping Review
In one paragraph

Article in Malaria journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Irene A KretchyDepartment of Pharmacy Practice and Clinical Pharmacy, University of Ghana School of Pharmacy, Accra, Ghana.
Deborah AtobrahCentre for Gender Studies and Advocacy, University of Ghana, Accra, Ghana.
David A AdumbireCentre for Gender Studies and Advocacy, University of Ghana, Accra, Ghana.
Samuel AnkamahUniversity of Ghana Library System, University of Ghana, Accra, Ghana.
Theodosia AdanuUniversity of Ghana Library System, University of Ghana, Accra, Ghana.
Delali M BadasuCentre for Gender Studies and Advocacy, University of Ghana, Accra, Ghana.
Benjamin K KwansaCentre for Gender Studies and Advocacy, University of Ghana, Accra, Ghana. bkkwansa@ug.edu.gh.

Funding

Bill and Melinda Gates Foundation INV-045184
6 · The paper itself

Abstract

backgroundMalaria infection in pregnancy is a critical determinant of maternal and neonatal health outcomes in endemic regions. Intermittent preventive treatment of malaria in pregnancy (IPTp) using sulfadoxine-pyrimethamine has been recommended by the World Health Organization (WHO), but its uptake remains low because of factors such as gender norms and expectations. However, interventions to optimize IPTp uptake, especially in malaria-endemic regions, have resulted in a decline in malaria during pregnancy, maternal and neonatal mortality, low birth weight, and placental parasitaemia. This scoping review aimed to synthesize evidence on IPTp uptake, particularly emphasizing gender-related strategies.

methodsThe modified version of Arksey and O'Malley's framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Reviews (PRISMA-ScR) were adopted for this review. Documents were retrieved from the following electronic databases and search engines: scopus, Web of Science, CINAHL Complete (EBSCO), PubMed, WHO, Global Index Medicus, and Google Scholar. The titles and abstracts of the publications were independently screened via Rayyan review management software, and the data were organized using the reach, effectiveness, adoption, implementation, and maintenance (RE-AIM) framework and gender analysis matrix.

resultsA total of 32 studies met the inclusion criteria. The most reported criterion was the effectiveness of the interventions, which demonstrated an increase in IPTp uptake after the intervention. The gender analysis framework revealed that involving both men and women in decision-making processes, empowering women, and promoting shared roles could improve the success of IPTp interventions.

conclusionsInterventions to increase IPTp uptake should be targeted at empowering women through education, increasing financial independence, and making decisions about their health.

Indexed as

AntimalarialsMalariaPregnancy Complications, ParasiticPyrimethamineSulfadoxineDrug CombinationsFemaleHumansMalePregnancySex FactorsAntimalarialsDrug Combinationsfanasil, pyrimethamine drug combinationPyrimethamineSulfadoxineGender rolesInterventionsIPTpMalaria-endemic regionsMalaria in pregnancyMalaria prevention and controlSub-Saharan AfricaSulfadoxine-pyrimethamine

Identifiers

PMID39966899
PMCPMC11837586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.