Evidence map›Paper›PMID 39966729›Full record

ArticleBasic and clinical andrology2025

Preoperative semen quality is superior to the quality shortly after orchiectomy in patients with testicular germ cell tumour - a retrospective study from two centres in Germany.

Klaus-Peter Dieckmann, Johanna Hochmuth-Tisch, Andrea Salzbrunn, Cord Matthies, Kathrein von Kopylow, Christian Wülfing, Uwe Pichlmeier, Armin Soave, Christian Guido Ruf

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Article in Basic and clinical andrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Klaus-Peter DieckmannAsklepios Klinik Altona, Urologische Abteilung, Hamburg, Germany.
Johanna Hochmuth-TischWestküstenklinikum Heide, Frauenklinik, Heide, Germany.
Andrea SalzbrunnKlinik und Poliklinik für Dermatologie und Venerologie, Bereich Andrologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Cord MatthiesAbteilung Urologie, Bundeswehrkrankenhaus Hamburg, Hamburg, Germany.
Kathrein von KopylowKlinik und Poliklinik für Dermatologie und Venerologie, Bereich Andrologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Christian WülfingAsklepios Klinik Altona, Urologische Abteilung, Hamburg, Germany.
Uwe PichlmeierInstitute of Medical Biometry and Epidemiology, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Armin Soave *Urologische Klinik und Poliklinik, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.
Christian Guido Ruf *Abteilung Urologie, Bundeswehrkrankenhaus Hamburg, Hamburg, Germany. Dr.Christianruf@gmx.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSperm cryopreservation in patients with testicular germ cell tumours (GCTs) is traditionally performed after orchiectomy. But, some evidence suggests preoperative semen quality to be superior. We aimed to clarify the optimal time-point of cryopreservation.In a retrospective study, semen quality of 163 patients analysed preoperatively was compared with 242 patients analysed shortly after orchiectomy. Descriptive statistical methods with standard tests for comparisons were employed along with stratified analyses regarding the influence of clinical factors.

resultsAll major semen parameters were significantly better in the preoperative group: median ejaculate volume (3 ml preoperatively vs. 2 ml postoperatively); median total sperm count (56.9 x10

conclusionsIn GCT patients, semen quality before orchiectomy is significantly superior to that found immediately after surgery. This superiority encompasses all major semen quality parameters. Of particular note is a threefold increase of azoospermia postoperatively. GCT patients are best advised to have cryopreservation performed before orchiectomy.

Indexed as

NonseminomaSemen qualitySeminomaSperm countSperm cryopreservationSperm motilityTesticular germ cell tumour

Identifiers

PMID39966729
PMCPMC11837636

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