ArticleBMC plant biology2025
Comparative metabolomic analysis provides insights into the metabolite profiles of wild and cultivated Dendrobium flexicaule.
Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Valorisation of the HalophyteFoods (Basel, Switzerland) · 2026Article
- Optimization of flavonoids extraction and elucidation of antioxidant mechanisms in Dendrobium flexicaule using metabolomics and machine learning.Ultrasonics sonochemistry · 2026Article
- Establishment of Regeneration Propagation Protocol Based on In Vitro Seeds Development of the Endangered Orchid SpeciesPlants (Basel, Switzerland) · 2026Article
- Metabolomic Profiling Reveals Geographical Origin, Tissue-Specific Specialization, and Environmental Plasticity in Secondary Metabolism ofMetabolites · 2026Article
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9 authors.
Funding
Abstract
backgroundDendrobium orchids (Dendrobium spp.) are valuable medicinal and attractive ornamental plants. Due to their limited wild resources, the size of the Dendrobium spp. population required for market demand primarily depends on artificial cultivation. However, the nutritional and therapeutic value of natural products may differ as growth conditions change. In this study, we profiled metabolites from wild and cultivated Dendrobium flexicaule (D. flexicaule) to explore the variations and interrelationships among bioactive components.
resultsA total of 840 annotated metabolites were discovered, 231 of which differed significantly between wild and cultivated D. flexicaule. A comparative investigation found that the types and amounts of metabolites, particularly flavonoids, lipids, amino acids and their derivatives, varied between wild and cultivated D. flexicaule. Using metabolite correlation analysis, a series of differentially abundant metabolites were found to be significantly correlated with phytohormones such as abscisic acid (ABA), salicylic acid (SA), and zeatins, indicating that plant hormones play a role in the accumulation of specific metabolites. Furthermore, many distinct metabolites were identified as key active ingredients of traditional Chinese medicines. Additionally, 78 components were discovered to be active pharmaceutical substances against various diseases, probably contributing to the diverse medical values of wild and cultivated D. flexicaule.
conclusionsOverall, comprehensively analyzed the metabolic profiles of wild and cultivated D. flexicaule in this study, serving as a theoretical and material foundation for quality control, health efficacy, and industrial development.
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