ArticleBMC geriatrics2025
Does low body weight mediate the relationship between tooth loss and cognitive impairment? A longitudinal cohort study of an older Chinese population.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association between cognitive impairment and comprehensive weight phenotypes among older adults in China: a nationwide survey.Aging clinical and experimental research · 2025Article
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10 authors.
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Abstract
objectiveOur study aimed to investigate the relationship between the number of teeth remaining and cognitive impairment among Chinese older adults, and to explore the role of low body weight in this association.
methodsData were drawn from 2011 to 2014 surveys of the Chinese Longitudinal Healthy Longevity Survey (CLHLS), involving 4056 respondents who had no cognitive decline and aged ≥ 65 years at baseline. Cognitive function was measured by the Mini-Mental Status Examination (MMSE), and the cognitive impairment was classified according to the length of education. Number of natural teeth was self-reported (classified as ≥ 20, 10-19, 1-9, and 0). Low body weight was defined as having a body mass index (BMI) of less than 18.5 kg/m
resultsComparing with participants with ≥ 20 teeth, 10-19 teeth and 1-9 teeth, those with 0 teeth (HR:2.14, 95% CI: 1.51, 3.03) were significantly associated with higher cognitive impairment risk in the fully adjusted model. Compared with denture users, the fully adjusted HR (95% CI) for non-denture users was 1.33 (1.04, 1.70). no teeth with non-denture users had the highest cognitive impairment risk (HR:1.63, 95% CI: 1.10, 2.41). Low body weight mediated 6.74% (ranging from 3.49 to 11%) of the association between the number of teeth remaining and cognitive impairment.
conclusionTooth loss increases the risk of cognitive decline, and low body weight partially mediates this association. CLINICAL TRIAL NUMBER: This is a retrospective cohort study targeting a population survey, which does not involve clinical trials and does not have clinical trial numbers.
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