ArticleJournal of cachexia, sarcopenia and muscle2025
Hand Grip Strength Cut-Off Points as a Discriminator of Sarcopenia and Sarcopenic Obesity: Results from the ELSA-Brasil Cohort.
Article in Journal of cachexia, sarcopenia and muscle, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Sarcopenia in Kidney Transplantation: Bridging Pathophysiology to Patient-Centered Care.Nutrients · 2026Review
- Dual-Energy X-Ray absorptiometry associates total body fat and bone mineral content with elevated blood pressure in adult divers.Scientific reports · 2026Article
- Lipedema and Dynapenia: Inflammatory Myosteatosis as a Mechanistic Link Between Tissue Expansion and Muscle Dysfunction.International journal of molecular sciences · 2026Review
- Vascular, physical fitness, lifestyle, and body composition characteristics in middle-aged and older diver fishermen: association between shear rate and lower-limb physical fitness.Frontiers in physiology · 2026Article
- Dietary Habits and Obesity in Middle-Aged and Elderly Europeans-The Survey of Health, Ageing, and Retirement in Europe (SHARE).Nutrients · 2025Article
- Bone mineral content determined by energy X-ray absorptiometry correlates with handgrip strength in Latin American divers.Frontiers in public health · 2025Article
- Examining Handgrip Strength in Persons Living With HIV in United States, Thailand, and South Africa: A Cross-Sectional Study.The Journal of the Association of Nurses in AIDS Care : JANACArticle
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13 authors.
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Abstract
backgroundHand grip strength (HGS) may represent an epidemiologically relevant alternative as an initial screening tool for sarcopenia and sarcopenic obesity. However, no study evaluated the performance capacity of HGS compared to other biomarkers in discriminating these conditions in adults.
objectiveThe study aimed to evaluate the performance of HGS as discriminator of sarcopenia and sarcopenic obesity, compared to urinary biomarkers of creatinine and potassium in 24 h for Brazilian adults.
methodsCross-sectional study. Women (n = 5431) and men (n = 6351) aged 38-79 years who participated in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) at second follow-up of the cohort (2012-2014). The area under the receiver operating characteristic curve (AUC) and the respective 95% confidence intervals were calculated for men and women in different age groups to assess the performance of HGS as a discriminator of sarcopenia and sarcopenic obesity, compared to the biomarkers of potassium and creatinine in urine in 24 h. The outcomes were classified based on the skeletal muscle mass index (BMI/height
resultsIt can be observed that 18.20% (15.51% women; 21.34% men) of the population showed a decline in skeletal muscle mass (sarcopenia). Of this total, 11.61% (10.52% women; 12.89% men) presented the isolated outcome of sarcopenia and 6.59% (4.99% women; 8.45% men) of sarcopenic obesity. The HGS areas under the ROC Curve ranged from 0.54 (CI = 0.493-0.596) to 0.76 (CI = 0.650-0.878) according to sex and age group. HGS performance compared to biomarkers was significantly higher in virtually all strata and outcomes analysed. The cut-off points that demonstrated greater accuracy and better performance in outcome discrimination were ≤ 42, ≤ 41, ≤ 38 and ≤ 36 kgf among males aged 38-44 years, 45-54 years, 55-64 years and 65-79 years, respectively. For women in the same age groups, HGS cut-offs were ≤ 26, ≤ 23, ≤ 23 and ≤ 21 kgf, respectively.
conclusionsThe results suggest that HGS is a good discriminator of sarcopenia and sarcopenic obesity, capable of achieving superior or equal performance to muscle mass biomarkers, especially in middle-aged adults.
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