Evidence map›Paper›PMID 39966602›Full record

SynthesisEye (London, England)2025

AI for glaucoma, Are we reporting well? a systematic literature review of DECIDE-AI checklist adherence.

Benedict Leonard-Hawkhead, Bethany E Higgins, David Wright, Augusto Azuara-Blanco

Abstract readSystematic Review
In one paragraph

Synthesis in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Progress in the Synthesis of Evidence in Glaucoma: What We Know and the Gaps that Remain.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benedict Leonard-HawkheadCentre for Public Health Queens University Belfast, Belfast, UK. bleonardhawkhead01@qub.ac.uk.ORCID http://orcid.org/0000-0003-1686-1107
Bethany E HigginsOptometry and Visual Sciences, School of Health Sciences, City, University of London, London, UK.
David WrightCentre for Public Health Queens University Belfast, Belfast, UK.ORCID http://orcid.org/0000-0001-8948-3691
Augusto Azuara-BlancoCentre for Public Health Queens University Belfast, Belfast, UK.ORCID http://orcid.org/0000-0002-4805-9322

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesThis systematic literature review examines the quality of early clinical evaluation of artificial intelligence (AI) decision support systems (DSS) reported in glaucoma care. Artificial Intelligence applications within glaucoma care are increasing within the literature. For such DSS, there needs to be standardised reporting to enable faster clinical adaptation. In May 2022, a checklist to facilitate reporting of early AI studies (DECIDE-AI) was published and adopted by the EQUATOR network.

methodsThe Cochrane Library, Embase, Ovid MEDLINE, PubMed, SCOPUS, and Web of Science Core Collection were searched for studies published between January 2020 and May 2023 that reported clinical evaluation of DSS for the diagnosis of glaucoma or for identifying the progression of glaucoma driven by AI. PRISMA guidelines were followed (PROSPERO registration: CRD42023431343). Study details were extracted and were reviewed against the DECIDE-AI checklist. The AI-Specific Score, Generic-Item Score, and DECIDE-AI Score were generated.

resultsA total of 1,552 records were screened, with 19 studies included within the review. All studies discussed an early clinical evaluation of AI use within glaucoma care, as defined by the a priori study protocol. Overall, the DECIDE-AI adherence score was low, with authors under reporting the AI specific items (30.3%), whilst adhering well to the generic reporting items (84.7%).

conclusionOverall, reporting of important aspects of AI studies was suboptimal. Encouraging editors and authors to incorporate the checklist will enhance standardised reporting, bolstering the evidence base for integrating AI DSS into glaucoma care workflows, thus help improving patient care and outcomes.

Indexed as

Artificial IntelligenceChecklistDecision Support Systems, ClinicalGlaucomaHumans

Identifiers

PMID39966602
PMCPMC11978933

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.