ArticleScientific reports2025
The power spectrum and functional connectivity characteristics of resting-state EEG in patients with generalized anxiety disorder.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Increased beta-band salience network connectivity predicts 12-month longitudinal changes in depressive and anxiety symptom severity in young adults: a resting-state EEG study.European archives of psychiatry and clinical neuroscience · 2026Article
- Ketamine effects on EEG and their links to therapy differ across treatment-resistant major depression, post-traumatic stress disorder, and obsessive-compulsive disorder.The international journal of neuropsychopharmacology · 2026Article
- A multifeature machine learning and resting-state EEG study reveals differences in beta oscillation in late-life depression with or without mild cognitive impairment.BMC psychiatry · 2026Article
- Attentional Impairments and Neural Compensation in Adolescents with High Social Anxiety Traits: A Combined ERP and Functional Connectivity Study.Journal of Intelligence · 2026Article
- An observational study to analyze changes in EEG alpha wave and alpha/beta ratio neurodynamics during an attention seeking cognitive task among young healthy adults with normal sleep and impaired sleep.Sleep & breathing = Schlaf & Atmung · 2026Article
- Quantitative electroencephalography as a next-generation tool in neurodiagnostics: significance, clinical applications, and practical interpretative frameworks.Frontiers in neuroscience · 2026Review
- Disrupted Global Brain Dynamics in Adolescents With Comorbid Anxiety and Depression: Neural Mechanisms and Classification Based on EEG Microstates.Depression and anxiety · 2026Article
- Neural mechanisms of uncertain decision-making in anxious adolescents: an EEG study based on the balloon analogue risk task.Frontiers in psychiatry · 2026Article
- A novel deep learning model for objective quantification of generalized anxiety disorder severity using EEG functional connectivity.Frontiers in psychiatry · 2026Article
- Local and network neural activations and their associations with sleep parameters during threat conditioning and extinction in persons with Generalized Anxiety Disorder with and without Insomnia Disorder.bioRxiv : the preprint server for biology · 2025Article
- Parietal Alpha Asymmetry as a Correlate of Internet Use Severity in Healthy Adults.Brain sciences · 2025Article
- Mapping EEG Metrics to Human Affective and Cognitive Models: An Interdisciplinary Scoping Review from a Cognitive Neuroscience Perspective.Biomimetics (Basel, Switzerland) · 2025Review
- Functional Magnetic Resonance Imaging-Based Analysis of Functional Connectivity in Chronic Stress: A Comparison of Stress-Induced and Recovery States.Brain sciences · 2025Article
- Research on the extension of respiratory interaction modalities in virtual reality technology and innovative methods for healing anxiety disorders.Scientific reports · 2025Article
- The role of prefrontal-hippocampal functional connectivity in schizophrenia-related cognitive dysfunction and the thalamic ventral midline involvement:Frontiers in neuroscience · 2025Review
- Multimodal assessment of acute stress dynamics using an aversive video paradigm (AVP).International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Recent studies have suggested a relationship between abnormal neurophysiological functions and generalized anxiety disorder (GAD). However, studies on its electrophysiological characteristics, such as its power spectrum and functional connectivity are relatively few and scattered than those on other mental disorders (e.g., depression, ADHD, etc.). The present study aims to reveal the multidimensional electrophysiological characteristics of GAD via comparative analysis of electroencephalogram (EEG) data between GAD patients and healthy controls. Specifically, resting-state EEG, with a duration of 10 min, was recorded from 98 GAD patients and 92 healthy control participants. The electrophysiological characteristics, including the power spectrum, alpha asymmetry, and functional connectivity, were extracted and compared between the two groups. The results revealed significantly increased beta-band activity; decreased ipsilateral fronto-temporal and parieto-temporal functional connectivities in the lower frequency bands (theta-beta band); as well as decreased frontal‒parietal and frontal‒occipital connectivities in the higher frequency bands (beta‒gamma band) in GAD patients. Additionally, alpha asymmetry analysis revealed a significantly greater rightward temporal alpha asymmetry in GAD patients. These findings suggest the existence of significant EEG characteristics in patients with GAD, supporting previous conclusions regarding abnormal neurophysiological functions in psychiatric disorders and potentially leading to the identification of biomarkers for clinical diagnosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.