Evidence map›Paper›PMID 39966497›Full record

ArticleNature communications2025

Sustainable pest management using plant secondary metabolites regulated azadirachtin nano-assemblies.

Xiaohong Zhang, Jianhua Xiao, Yuqi Huang, Yulu Liu, Gaohua Hu, Weiyao Yan, Guangyao Yan, Qing Guo, Jiawei Shi, Ruyue Han and 3 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Toward Sustainable Pesticide Application: Bridging Efficacy and Food Safety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  13. Article
  14. Article
  15. The Discovery of Potential Repellent Compounds forInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xiaohong ZhangCollege of Plant Protection, China Agricultural University, Beijing, China.ORCID http://orcid.org/0000-0002-1910-194X
Jianhua XiaoCollege of Plant Protection, China Agricultural University, Beijing, China.
Yuqi HuangCollege of Plant Protection, China Agricultural University, Beijing, China.
Yulu LiuCollege of Plant Protection, China Agricultural University, Beijing, China.
Gaohua HuCollege of Plant Protection, China Agricultural University, Beijing, China.
Weiyao YanCollege of Plant Protection, China Agricultural University, Beijing, China.
Guangyao YanCollege of Plant Protection, China Agricultural University, Beijing, China.
Qing GuoCollege of Plant Protection, China Agricultural University, Beijing, China.
Jiawei ShiCollege of Plant Protection, China Agricultural University, Beijing, China.
Ruyue HanCollege of Plant Protection, China Agricultural University, Beijing, China.
Jianqiang LiCollege of Plant Protection, China Agricultural University, Beijing, China.
Gang TangCollege of Plant Protection, China Agricultural University, Beijing, China. tgkobe@163.com.ORCID http://orcid.org/0000-0002-2093-0075
Yongsong CaoCollege of Plant Protection, China Agricultural University, Beijing, China. caoysong@126.com.ORCID http://orcid.org/0000-0003-2110-8072

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biopesticides have emerged as a global trend to minimize the risks associated with synthetic agrochemicals. However, their stability and efficacies remain challenges for widespread application. Herein, co-assembled nanoparticles (AT NPs or AP NPs) based on azadirachtin (AZA) and tannic acid (TA) or phenylalanine (PA) are constructed in aqueous solution through self-assembly technology. The small particle size, low PDI, high ζ-potential, and related other physicochemical characteristics of nanoparticles can improve wettability, adhesiveness, rain erosion resistance, and photostability compared to the commercial AZA formulation. Importantly, co-assemblies with bidirectional pH-responsive disassembly in acidic or alkaline solutions, allow them to respond to microenvironmental stimuli of targets and enable controlled release of AZA. The nanosystems demonstrated remarkable in vitro and in vivo insecticidal activities against Ostrinia furnacalis and Aphis gossypii. This study illustrates a distinctive perspective for developing eco-friendly nanosystems, highlighting a water-based treatment method for biopesticides with improved physicochemical properties and utilization efficiency.

Indexed as

InsecticidesLimoninsNanoparticlesPest Control, BiologicalAnimalsHemipteraHydrogen-Ion ConcentrationMothsParticle SizePhenylalanineSecondary MetabolismTanninsWettabilityazadirachtinInsecticidesLimoninsPhenylalanineTannins

Identifiers

PMID39966497
PMCPMC11836458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.