Evidence map›Paper›PMID 39966444›Full record

ArticleScientific reports2025

Development and clinical validation of a novel platelet count-based nomogram for predicting microvascular invasion in HCC.

Wenjie Zheng, Haoqi Chen, Jianfeng Zhang, Kaiming He, Wenfeng Zhu, Xiaolong Chen, Xijing Yan, Zexin Lin, Yang Yang, Xiaowen Wang and 2 more

Abstract readValidation Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wenjie Zheng *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Haoqi Chen *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Jianfeng Zhang *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Kaiming He *Department of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Wenfeng ZhuDepartment of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510220, China.
Xiaolong ChenDepartment of Hepatobiliary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.
Xijing YanDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Zexin LinDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Yang YangDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China.
Xiaowen WangDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China. wangxw68@mail3.sysu.edu.cn.
Hua LiDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China. lihua3@mail.sysu.edu.cn.
Shuguang ZhuDepartment of Hepatic Surgery, Liver Transplantation, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510630, China. za200909@163.com.

Funding

National Natural Science Foundation of China 82270688, 82100691Natural Science Foundation of Guangdong Province 2021A1515010726
6 · The paper itself

Abstract

We aimed to develop a convenient nomogram to predict preoperative MVI in patients with hepatocellular carcinoma (HCC). Patients who underwent surgical resection due to HCC from June 2018 to June 2023 at the Third Affiliated Hospital of Sun Yat-sen University were retrospectively reviewed. Univariate and multivariable logistic linear regression analyses were used to investigate potential risk factors for MVI. A nomogram was plotted based on these risk factors. The tumor diameter (≥ 5 cm), BCLC stage, PLT (>127.50 × 10

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsMicrovesselsNomogramsAdultAgedFemaleHumansMaleMiddle AgedNeoplasm InvasivenessPlatelet CountRetrospective StudiesRisk FactorsHepatocellular carcinomaMicrovascular InvasionNomogramPlatelet

Identifiers

PMID39966444
PMCPMC11836223

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.