ArticleScientific reports2025
Photodynamic therapy in non-surgical treatment of periodontitis.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Syntheses, DNA interactions, and photodynamic antimicrobial properties of near-infrared indolium carbocyanine dyes.RSC advances · 2026Article
- Hypericin-Mediated Antimicrobial Photodynamic Therapy in Dentistry: A Systematic Review of Applications Against Oral Biofilms and Infections.Pharmaceutics · 2026Review
- Light-Activated Metal-Dependent Protein Degradation: A Heterobifunctional Ruthenium(II) Photosensitizer Targeting New Delhi Metallo-β-lactamase 1.Journal of the American Chemical Society · 2025Article
- Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a chronic inflammation disease that, apart from caries, remains the main cause of tooth loss, that lead to a deterioration of the quality of life. Non-surgical treatment is the basic form of periodontal therapy, regardless of the stage of the disease. Novel supportive treatment methods are constantly implemented to improve the effects of non-surgical treatment, including photodynamic therapy that leads to a selective photosensitization of bacteria with the simultaneous participation of a photosensitizer applied into the periodontal pocket. The aim of the study is to evaluate the use of adjunctive photodynamic therapy on clinical and microbiological parameters in the non-surgical treatment of periodontitis. The clinical study involved 30 generally healthy, non-smoking patients. After a periodontal examination standard non-surgical treatment was applied. 6 weeks later a control periodontal clinical examination was performed and then periodontal pockets were subjected to a photodynamic therapy (PDT) using the FotoSan 630 cm Dental lamp with a perio tip and the FotoSan agent CMS Dental medium density photosensitizer. A significant improvement in clinical parameters including BoP (reduction 73,3%, p < 0,05), PD (reduction 1,9 mm, p < 0,05) and CAL (gain 0,6 mm, p < 0,05) and a significant reduction of red complex bacteria after application of PDT compared to SRP alone was observed. The application of supportive photodynamic therapy improve the effectiveness of periodontal non-surgical treatment including clinical parameters and reduction in subgingival bacteria biofilm.
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