Evidence map›Paper›PMID 39966415›Full record

ArticleScientific reports2025

Substance use during pregnancy and childhood dental caries: a Brazilian cohort study.

Elisa Miranda Costa, Daniela Silva Tomaz, Francenilde Silva de Sousa, Álvaro Fonseca Thomaz, Soraia de Fátima Carvalho Souza, Cecilia Claudia Costa Ribeiro, Claudia Maria Coelho Alves, Erika Barbara Abreu Fonseca Thomaz

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elisa Miranda CostaDepartment of Public Health, Federal University of Maranhão, São Luís, Maranhão, Brazil. elisa.costa@foufal.ufal.br.
Daniela Silva TomazDepartment of Public Health, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Francenilde Silva de SousaDepartment of Public Health, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Álvaro Fonseca ThomazDepartment of Psychology, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Soraia de Fátima Carvalho SouzaDepartment of Dentistry, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Cecilia Claudia Costa RibeiroDepartment of Public Health, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Claudia Maria Coelho AlvesDepartment of Public Health, Federal University of Maranhão, São Luís, Maranhão, Brazil.
Erika Barbara Abreu Fonseca ThomazDepartment of Public Health, Federal University of Maranhão, São Luís, Maranhão, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 306592/2018-5Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001FAPEMA/CNPQ nº 20/2022Josue Montello Foundation 025524/2021-54
6 · The paper itself

Abstract

This study aimed to evaluate the association between substance use during pregnancy (SUDP) and dental caries considering the Tooth Development Hypothesis and the Behavioral Hypothesis. This is a Brazilian cohort study conducted on 865 children (12-36 months). Exposure to SUDP was the latent variable and consisted of the use of alcohol, tobacco, and illicit drugs. The dependent variable was the number of dental caries lesions according to the Nyvad criteria. Structural equation modeling was used for analysis, estimating the standardized coefficient (SC) in two models: traditional (1) and with bias-corrected bootstrap estimates (2). The models were adjusted for socioeconomic status (SES), child's age, maternal age, symptoms of minor psychiatric disorders, sugar consumption, feeding, developmental defects of enamel, and gingival bleeding on brushing (GBoB) (α = 5%). SUDP did not affect dental caries. SES (SC

Indexed as

Dental CariesPrenatal Exposure Delayed EffectsSubstance-Related DisordersAdultBrazilChild, PreschoolCohort StudiesFemaleHumansInfantMalePregnancyRisk FactorsAlcoholDental cariesIllicit drugsPregnant womenSubstance abuse

Identifiers

PMID39966415
PMCPMC11836313

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.