Evidence map›Paper›PMID 39966301›Full record

ReviewTopics in current chemistry (Cham)2025

Understanding the Electrochemical MOF Sensors in Detecting Cancer with Special Emphasis on Breast Carcinoma Biomarkers.

Brij Mohan, Krunal Modi, Gurjaspreet Singh, Anup Paul, Ismayil M Garazade, Armando J L Pombeiro, Xuefeng Liu, Wei Sun, Sang Sub Kim

Abstract readReview
PubMed Publisher
In one paragraph

Review in Topics in current chemistry (Cham), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Brij MohanCentro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisbon, Portugal. brij.mohan@tecnico.ulisboa.pt.
Krunal ModiElectronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, People's Republic of China.
Gurjaspreet SinghDepartment of Chemistry and Centre of Advanced Studies, Panjab University, Chandigarh, 160014, India. gjpsingh@pu.ac.in.
Anup PaulCentro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisbon, Portugal.
Ismayil M GarazadeCentro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisbon, Portugal.
Armando J L PombeiroCentro de Química Estrutural, Institute of Molecular Sciences, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisbon, Portugal.
Xuefeng LiuElectronic and Optical Engineering, Nanjing University of Science and Technology, Nanjing, 210094, People's Republic of China.
Wei SunHainan International Joint Research Center of Marine Advanced Photoelectric Functional Materials, Key Laboratory of Laser Technology and Optoelectronic Functional Materials of Hainan Province, College of Chemistry and Chemical Engineering, Hainan Normal University, Haikou, 571158, China.
Sang Sub KimDepartment of Materials Science and Engineering, Inha University, 100 Inha-ro, Incheon, 22212, Republic of Korea. sangsub@inha.ac.kr.

Funding

Fundação para a Ciência e a Tecnologia UIDB/00100/2020 (DOI:10.54499/UIDB/00100/2020), UIDP/00100/2020 (DOI:10.54499/UIDP/00100/2020), and LA/P/0056/2020 (DOI:10.54499/LA/P/0056/2020)
6 · The paper itself

Abstract

Cancer is a disease that claims millions of lives each year, often because early symptoms go unnoticed, a situation which severely impacts society. Point-of-care biosensors using metal-organic frameworks (MOFs) have the power to transform cancer biomarker detection due to their exceptional structural and conductive properties. This review discusses the electrochemical sensor's design and development of electroactive MOF materials with mechanistic insights. It highlights recent advancements in utilizing MOF composites to effectively detect cancer biomarkers in real samples. The emphasis on the critical application of MOFs in breast cancer biomarker detection presents its importance for women's health. The review thoroughly examines the adjustable structures, porosity, and fabrication capabilities of MOFs in identifying cancer biomarkers. It provides a detailed analysis of methods to enhance the sensitivity and applicability of MOF composites for cancer detection. Furthermore, the review explores strategies to boost sensor performance, tackles existing challenges head-on, and outlines promising prospects. It emphasizes the urgent need for advanced cancer detection tools and aims to motivate researchers to develop innovative solutions.

Indexed as

Biomarkers, TumorBiosensing TechniquesBreast NeoplasmsElectrochemical TechniquesMetal-Organic FrameworksFemaleHumansBiomarkers, TumorMetal-Organic FrameworksBreast cancerElectrochemical biosensorsMOF compositesQuantifying stimuli-responsiveSignal changes

Identifiers

PMID39966301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.