Evidence map›Paper›PMID 39966287›Full record

ArticleDigestive diseases and sciences2025

Effect of Cholecystectomy on Bubble Formation and Endoscopic Visualization: A Retrospective Cohort Study.

Jeffrey Loeffler, Gaetano Di Pietro, Hamed Chehab, Mira AlSheikh, Harika Kandlakunta, Hassan Al Moussawi, Danial Daneshvar, Yosef Buchen, Dineshreddy Gurala, Shivantha Amarnath and 4 more

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Article in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jeffrey LoefflerDepartment of Internal Medicine, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA. jloeffler@northwell.edu.
Gaetano Di PietroDepartment of Internal Medicine, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Hamed ChehabDepartment of Internal Medicine, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Mira AlSheikhDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Harika KandlakuntaDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Hassan Al MoussawiDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Danial DaneshvarDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Yosef BuchenDepartment of Internal Medicine, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Dineshreddy GuralaDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Shivantha AmarnathDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Mohammad AbureeshDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Ahmed ElfikyDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Vivek GumasteDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.
Sherif AndrawesDepartment of Gastroenterology and Hepatology, Northwell Health-Staten Island University Hospital, Staten Island, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate the association between cholecystectomy and colonic bubble formation during colonoscopy,

methodsA single-center retrospective cohort study was conducted at Staten Island University Hospital. Researchers reviewed 348 colonoscopy reports, comparing patients with (n = 56) and without (n = 292) a history of cholecystectomy. Colonic bubble formation was assessed using a 0-3 scale (0 = no bubbles, 3 = severe bubbles). Secondary endpoints included polyp and adenoma detection, withdrawal and procedure times, bowel preparation quality, and repeat procedures. Statistical analysis included t-tests, Mann-Whitney U tests, and χ

resultsPatients with prior cholecystectomy had significantly higher incidence of severe bubble formation (score 3; 28.6% vs. 12%, p = 0.001), longer withdrawal times (18 ± 8 vs. 15 ± 5 min, p = 0.024), and increased need for repeat colonoscopies (10.7% vs. 2.1%, p = 0.001). No significant differences were found in adenoma detection, polyp detection, or bowel preparation quality between the two groups.

conclusionCholecystectomy is associated with increased colonic bubble formation during colonoscopy, leading to longer withdrawal times and higher rates of repeat procedures. While this study did not find a difference in adenoma detection rates, the impaired visualization caused by bubbles may necessitate tailored bowel preparation strategies for patients with a history of cholecystectomy to optimize colonoscopy effectiveness.

Indexed as

AdenomaCholecystectomyColonic PolypsColonoscopyAgedFemaleHumansMaleMiddle AgedRetrospective StudiesBowel PreparationCholecystectomyColonic BubblesColonoscopyEndoscopy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.