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ArticleHernia : the journal of hernias and abdominal wall surgery2025

Postoperative outcomes and wound events in incisional hernia repair using hybrid mesh: results from a prospective multicenter italian study.

Francesco Pizza, Antonio Iuppa, Pietro Maida, Vincenzo Pilone, Antonio Crucitti, Tomaiuolo Pasquina Maria Carmen, Lorenzo Morini, Jacopo Nicoló Marin, Tommaso Petitti, Camillo Bertoglio and 8 more

Registry-linked trialAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06166069 (Early Surgical Outcomes in the Use of Hybrid Mesh for Incisional Hernia Repair), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06166069 completednot on this map

Early Surgical Outcomes in the Use of Hybrid Mesh for Incisional Hernia Repair: Results From a Multicenter Italian Study

TypeobservationalSponsorAzienda Sanitaria Locale Napoli 2 NordRan2021 to 2023Enrolled272ConditionsHernia, Incisional Hernia, Laparoscopic
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Francesco PizzaAsl Napoli2 Nord Department of Surgery, Hospital 'Rizzoli', Naples, Italy. francesco_pizza@libero.it.ORCID 0000-0001-9785-4405
Antonio IuppaDivision of Surgery, Mediterranean Oncologic Institute, Catania, Italy.
Pietro MaidaCasa Di Cura Privata Malzoni, Surgery Avellino, Campania, Italy.
Vincenzo PilonePublic Health Department, Naples "Federico II" University, AOU "Federico II" - via S.Pansini 5, Naples, Italy.
Antonio CrucittiU.O.C. Di Chirurgia Generale 1 Fondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy.
Tomaiuolo Pasquina Maria CarmenU.O.C. Di Chirurgia Generale 1 Fondazione Policlinico Universitario Agostino Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy.
Lorenzo MoriniDivision of General and Oncologic Surgery, ASST "Grande Ospedale Metropolitano" Niguarda, Milan, Italy.
Jacopo Nicoló MarinDivision of General and Oncologic Surgery, ASST "Grande Ospedale Metropolitano" Niguarda, Milan, Italy.
Tommaso PetittiDivision of General, Surgery Hospital San Severo Foggia, San Severo, Italy.
Camillo BertoglioDivision of General Surgery, ASST Ovest Milanese, Hospital of Magenta, 20013, Magenta, Italy.
Gianpaolo MarteDivision of General Surgery Ospedale del Mare, Naples, Italy.
Ignazio SordelliCasa Di Cura Privata Malzoni, Surgery Avellino, Campania, Italy.
Simona GiliAsl Napoli3 Sud Department of Surgery, Hospital 'San Leonardo', Castellammare, Italy.
Francesco Saverio LucidoItaly 3Division of General, Mininvasive and Bariatric Surgery, Campania 'Luigi Vanvitelli', Naples, Italy.
Lugi BuscianoItaly 3Division of General, Mininvasive and Bariatric Surgery, Campania 'Luigi Vanvitelli', Naples, Italy.
Dario D'AntonioAsl Napoli2 Nord Department of Surgery, Hospital 'Rizzoli', Naples, Italy.
Ludovico DocimoItaly 3Division of General, Mininvasive and Bariatric Surgery, Campania 'Luigi Vanvitelli', Naples, Italy.
Claudio GambardellaItaly 3Division of General, Mininvasive and Bariatric Surgery, Campania 'Luigi Vanvitelli', Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe complexity of managing ventral hernias leads surgeons to explore different optimal techniques and mesh selection. Hybrid meshes, combining absorbable and permanent components, aim to balance long-term durability and infection risk. This study evaluated the extended-term outcomes of GORE

methodsConducted across eight Italian surgery centers from January 2020 to September 2022, this multicenter analysis prospectively assessed the outcomes of patients undergoing laparoscopic repair of incisional hernias using GORE® SYNECOR. Outcomes included postoperative wound events, pain, recurrence, and mesh bulging.

resultsA total of 371 patients participated in the study. No serious adverse events or significant mesh-related complications were observed. Surgical site occurrences (SSO) were recorded in a proportion of cases, and hernia sac volume was identified as the only independent risk factor (p < 0.0001). At three months post-surgery, pain levels and impacts on daily activities were minimal. At 24 months, recurrence and mesh bulging were associated only with patients with hernia sac sizes larger than 450 cm

conclusionLaparoscopic incisional hernia repair using GORE CLINICALTRIALS: NCT06166069.

Indexed as

Hernia, VentralHerniorrhaphyIncisional HerniaLaparoscopyPostoperative ComplicationsSurgical MeshAdultAgedFemaleHumansItalyMaleMiddle AgedPostoperative PainProspective StudiesRecurrenceHybrid meshIncisional herniaIPOM plusIPOM standard

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.