Evidence map›Paper›PMID 39966167›Full record

ArticleClinical neuroradiology2025

Mechanical Thrombectomy for Middle Cerebral Artery Medium Vessel Occlusions Using Single Plane Angiography.

Krishna Amuluru, Jimmy Nguyen, Andrew DeNardo, John Scott, Daniel Gibson, Fawaz Al-Mufti, Dileep Yavagal, Daniel H Sahlein

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Krishna AmuluruAscension St. Vincent Medical Center, Division of Interventional Neuroradiology, Goodman Campbell Brain and Spine, Indianapolis, IN, USA. kamuluru@goodmancampbell.com.ORCID http://orcid.org/0000-0002-8859-8574
Jimmy NguyenDepartment of Radiology, Indiana University School of Medicine, Indianapolis, IN, USA.
Andrew DeNardoAscension St. Vincent Medical Center, Division of Interventional Neuroradiology, Goodman Campbell Brain and Spine, Indianapolis, IN, USA.
John ScottAscension St. Vincent Medical Center, Division of Interventional Neuroradiology, Goodman Campbell Brain and Spine, Indianapolis, IN, USA.
Daniel GibsonAscension St. Vincent Medical Center, Division of Interventional Neuroradiology, Goodman Campbell Brain and Spine, Indianapolis, IN, USA.
Fawaz Al-MuftiDepartment of Endovascular Neurosurgery and Neurocritical Care, Westchester Medical Center, Valhalla, NY, USA.
Dileep YavagalClinical Neurology and Neurosurgery, University of Miami and Jackson Memorial Hospitals, Miami, FL, USA.
Daniel H SahleinAscension St. Vincent Medical Center, Division of Interventional Neuroradiology, Goodman Campbell Brain and Spine, Indianapolis, IN, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeEndovascular thrombectomy is now the standard of care for large vessel occlusion acute ischemic stroke. However, acute stroke due to medium-vessel occlusions often result in unfavorable outcomes, and guidelines for thrombectomy are lacking. Moreover, nearly all clinical data and thrombectomy trials are based on biplane angiography systems. This study aims to compare the safety and efficacy of stroke thrombectomy procedures performed on single-plane versus biplane angiography systems in patients presenting with medium-vessel occlusions of the middle cerebral artery. MATERIALS AND

methodsThis retrospective study included consecutive patients with acute ischemic stroke due to primary middle cerebral artery medium-vessel occlusions treated with thrombectomy between 7/1/2020 and 8/1/2022 at a single high-volume practice. Patients were dichotomized into those treated on single plane and biplane systems. Demographic, procedural, clinical and follow-up characteristics were compared.

resultsAmong the 149 patients included, 44 underwent thrombectomy on single-plane systems, and 93 on biplane systems. No significant differences were detected in rates of good functional outcomes (mRS < 2; SP 54% vs BP 42%, p = 0.19), successful recanalization (TICI ≥ 2B; SP 91% vs BP 86%, p = 0.77), intra-procedural vascular injury (SP 0% vs BP 3%; p = 0.56), or time from groin puncture to reperfusion (SP 25 min vs BP 27 min; p = 0.97). No significant differences were detected in peri-procedural complications, or symptomatic intracerebral hemorrhage.

conclusionThrombectomy for middle cerebral artery medium-vessel occlusions performed on single-plane angiography systems is as safe and efficacious as biplane procedures. Our results may have implications for increasing access to care, especially in regions with limited resources.

Indexed as

Cerebral AngiographyInfarction, Middle Cerebral ArteryThrombectomyAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeAcute ischemic strokeBi-planeMedium-vessel-occlusionSingle-planeStroke thrombectomy

Identifiers

PMID39966167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.