Evidence map›Paper›PMID 39966147›Full record

ReviewHerzschrittmachertherapie & Elektrophysiologie2025

[Physiological pacing and heart failure : Hope or hype?]

Victoria Johnson, Carlos Antepara, Reza Wakili, Jörn Schmitt

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Herzschrittmachertherapie & Elektrophysiologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Victoria JohnsonUniversitäres Herzzentrum, ZIM III, Abteilung für Kardiologie, Universitätsmedizin Frankfurt, Theodor-Stern-Kai 7, 60596, Frankfurt, Deutschland. Victoria.johnson@herz-frankfurt.de.
Carlos AnteparaWestpfalzklinikum Kaiserslautern, Hellmut-Hartert-Srasse 1, 67655, Kaiserslautern, Deutschland.
Reza WakiliUniversitäres Herzzentrum, ZIM III, Abteilung für Kardiologie, Universitätsmedizin Frankfurt, Theodor-Stern-Kai 7, 60596, Frankfurt, Deutschland.
Jörn SchmittUniversitäres Herzzentrum, ZIM III, Abteilung für Kardiologie, Universitätsmedizin Frankfurt, Theodor-Stern-Kai 7, 60596, Frankfurt, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The cornerstone of heart failure treatment consists of a four pillar drug therapy. Patients with existing heart failure and complete left bundle branch block, or patients with an indication for pacemaker therapy for bradycardia and heart failure, benefit from physiological stimulation. For patients with left bundle branch block and severely impaired left ventricular systolic pump function (HFrEF), cardiac resynchronisation therapy (CRT) has so far been the gold standard. However, it is now increasingly possible to stimulate the conduction system directly using new forms of stimulation and to achieve similar clinical results. At present, left bundle branch area pacing (LBBAP) is the form of stimulation most frequently investigated in clinical studies. A special situation arises in the case of pacemaker-induced cardiomyopathy with right ventricular apical pacing. Here, LBBAP is certainly a beacon of hope.

Indexed as

Bundle-Branch BlockCardiac Pacing, ArtificialCardiac Resynchronization TherapyHeart FailureEvidence-Based MedicineHumansTreatment OutcomeCardiac pacemakerCardiac resynchronisation therapyHeart failureLeft ventricular stimulationPhysiological stimulation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.