ArticleSurgical endoscopy2025
Closure strength of endoscopic hand-suturing in ex vivo porcine gastric ESD defect models: an exploratory animal study.
Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundEndoscopic hand-suturing (EHS) has been used to close gastrointestinal defects following endoscopic submucosal resection (ESD), but its closure strength needs further evaluation. This exploratory animal study aimed to compare the closure strength of EHS and titanium clips in ex vivo porcine gastric ESD defect models.
methodsFifteen porcine stomachs were used to create ESD defect models, each featuring a 2-3-cm defect in the gastric body and another in the antrum. Defects were randomly assigned to three groups: EHS group (Group A), dense clipping group (Group B), and loose clipping group (Group C). Under endoscopy, Group A defects were sutured with 4 stitches, Group B with 7 clips, and Group C with 4 clips. The primary outcome measures were overall closure strength and closure strength per unit length, measured with a digital spring scale. Differences among groups were analyzed with the Kruskal-Wallis H test.
resultAll 30 defects were successfully closed endoscopically. Group A achieved significantly higher overall closure strength [1.06 kg (0.96 kg, 1.22 kg)] compared to Group B [0.27 kg (0.19 kg, 0.31 kg), P = 0.026] and Group C [0.11 kg (0.09 kg, 0.15 kg), P < 0.001]. For the closure strength per unit length, Group A [0.33 kg (0.27 kg, 0.35 kg)] also outperformed Group B [0.08 kg (0.06 kg, 0.10 kg), P = 0.023] and Group C [0.04 kg (0.03 kg, 0.04 kg), P < 0.001].
conclusionEHS can provide superior closure strength for ex vivo gastric ESD defects compared to simple titanium clips.
Indexed as
Identifiers
39966124What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.