ArticleBMJ (Clinical research ed.)2025
Discrepancies in neglected tropical diseases burden estimates in China: comparative study of real-world data and Global Burden of Disease 2021 data (2004-2020).
Article in BMJ (Clinical research ed.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global, regional, national burden of colorectal cancer from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021.Frontiers in oncology · 2025Pooled it
- Trends and burden of maternal disorders in China from 1990 to 2023: Analysis of the Global Burden of Disease Study 2023.Chinese medical journal · 2026Article
- Epidemiological transitions of Visceral Leishmaniasis in G20 countries: A 33-year retrospective joinpoint and demographic decomposition analysis with 20-year ARIMA projections.PLoS neglected tropical diseases · 2026Article
- A cost-outcome assessment of dog deworming for echinococcosis control in the Xizang Autonomous Region, China, 2016-2022.PLoS neglected tropical diseases · 2026Article
- Global health perspectives on diet patterns micronutrients and climato-economic factors.iScience · 2026Article
- Publication Characteristics and Reporting Quality of GBD-Derived Burden of Disease Studies: A Cross-Sectional Analysis of Lung Cancer.Journal of evidence-based medicine · 2026Article
- Global patterns of pertussis incidence and vaccination strategies: implications of divergent surveillance data.NPJ vaccines · 2026Article
- Trends and Burden of Human Rabies in Iran 2012-2021: A Cross-Sectional Study.Health science reports · 2026Article
- Diseases Caused by Parasites with Invertebrate Hosts in China: Burden and Trends of Leishmaniasis and Schistosomiasis.Pathogens (Basel, Switzerland) · 2026Article
- Trends in the burden of road traffic injuries among children and adolescents aged 0-19 years in low- and middle-income countries, 1990-2023.Journal of global health · 2026Article
- Prediction of 6-year mortality in advanced splenomegaly-subtype schistosomiasis: a retrospective cohort study from Hubei, China.BMJ open · 2026Article
- SFTS exerts an underrecognized disease burden and socioeconomic effect in East Asia.Biosafety and health · 2026Article
- Effects of recombinantFrontiers in cellular and infection microbiology · 2026Article
- Potential Causal Association Between Plasma Lipidomes and Keloid: Analysis from a Two-Sample Mendelian Randomization.Clinical, cosmetic and investigational dermatology · 2026Article
- Global, regional, and national burden of tuberculosis, 1990-2050: a systematic comparative analysis based on retrospective cross-sectional of GBD 2021 and WHO surveillance systems.International journal of surgery (London, England) · 2026Article
- Using a novel hybrid AI-based paper-to-digital pipeline for extracting patient-level clinical data from routine hospital records in Kenya: a retrospective multicentre study.BMJ digital health & AI · 2026Article
- The Global Economic Burden of Tuberculosis: Regional Disparities and Implications.Open forum infectious diseases · 2026Article
- The declining but persistent burden of lower respiratory infections from secondhand smoke in children aged under 14 years: Global trends 1990-2021 and forecasts to 2035, based on a secondary dataset analysis of Global Burden of Disease (GBD) 2021.Tobacco induced diseases · 2026Article
- The burden of low back pain and predictions in Asia-Pacific region, 1990-2021: a comparative analysis of China, Japan, Thailand, and Pakistan.Frontiers in medicine · 2026Article
- TIGIT impairs NK cell antifibrotic activity through the IFNγ-IFI30 axis in schistosomiasis-induced liver fibrosis.Frontiers in immunology · 2026Article
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7 authors.
Funding
Abstract
objectivesTo assess the discrepancies between real-world data and the Global Burden of Disease (GBD) 2021 estimates for six neglected tropical diseases in China. Additionally, to evaluate the applicability of the GBD model within the Chinese context and to assess the effectiveness of China's historical prevention and control policies for neglected tropical diseases.
designComparative study of real-world data and GBD 2021 (2004-2020).
main outcome measuresDisability adjusted life years (DALYs).
methodsDALYs based on reported data for leprosy, echinococcosis, schistosomiasis, visceral leishmaniasis, dengue, and rabies from 2004 to 2020 were compared with the estimated DALYs from the GBD 2021 database. Additionally, we combined and analysed China's historical policies on prevention and control of neglected tropical diseases with real-world DALYs. DATA SOURCES: Reported data were sourced from the Chinese Center for Disease Control and Prevention's China Public Health Science data centre and related reports. Data for GBD 2021 and GBD 2019 were obtained from GBD databases. These data included all of China's 31 provinces (including autonomous regions and municipalities) and the Xinjiang Production and Construction Corps.
resultsThe total real-world DALYs based on reported data of six neglected tropical diseases decreased from 260 000 person years in 2004 to 19 000 person years in 2020, with a 93% (241 000/260 000 person years) reduction. The 17 year average real-world DALYs from 2004 to 2020 versus the GBD 2021 estimates for the same period were 42
conclusionsThe findings indicate that reliance solely on global estimates, such as those of the GBD, may not sufficiently capture the dynamics of neglected tropical diseases in China. Integrating local epidemiological data into global health assessments is crucial to develop accurate and effective public health policies. This study highlights the importance of continuously updating and improving data collection and surveillance methods to adapt public health strategies to evolving disease patterns.
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