Evidence map›Paper›PMID 39965574›Full record

ArticleCurrent biology : CB2025

Attention to memory content enhances single-unit spike sequence fidelity in the human anterior temporal lobe.

Kelsey K Sundby, Alex P Vaz, John H Wittig, Samantha N Jackson, Sara K Inati, Kareem A Zaghloul

Abstract read
In one paragraph

Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelsey K SundbySurgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA.
Alex P VazSurgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA; Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA 19104, USA.
John H WittigSurgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA.
Samantha N JacksonSurgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA.
Sara K InatiSurgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA.
Kareem A ZaghloulSurgical Neurology Branch, NINDS, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: kareem.zaghloul@nih.gov.

Funding

Investigating the neural mechanisms of human cognitive function through intracranial recordingsZIANS003144 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI ZAGHLOUL, KAREEM · 2014 to 2025
$36.1M
Intramural NIH HHS Z99 NS999999Intramural NIH HHS ZIA NS003144
6 · The paper itself

Abstract

Attention aids in prioritizing information relevant to our present goals. For example, attention may augment sensory processing by modulating neural activity for low-level features of the attended items. Attention can also prioritize the contents of memory, facilitating our ability to remember some pieces of information while ignoring others. Here, we examine how using attention to modulate the contents of memory affects temporally organized sequences of neuronal spiking in the human anterior temporal lobe. These spike sequences represent higher-level semantic information and occur repeatedly and consistently as participants process and encode words into memory. Our results demonstrate that attention deployed to prioritize words for memory increases the consistency of these spike sequences. Further, retroactively cueing words elicits the replay of these sequences. Our data, therefore, suggest that paying attention to prioritizing semantic content for memory may improve the temporal organization of neural spiking representations of semantic information in the anterior temporal lobe.

Indexed as

Action PotentialsAttentionMemoryNeuronsTemporal LobeAdultCuesFemaleHumansMaleSemanticsYoung Adultattentionmemorysingle-unit spiking

Identifiers

PMID39965574
PMCPMC11903144

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.