Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
25 authors.
Mathilde GagliardiniUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0009-0001-0399-4667
Sabrina MechaussierUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0002-3801-2416
Carolina Campos PinaUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0003-0105-2198
Monica MoraisUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0003-3226-3828
Olivier PostalUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0002-6911-7552
Philippe JeanUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0001-5325-1370
Typhaine DupontUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.
Amrit Singh-EstivaletUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Auditory Therapies Innovation Laboratory, Paris, F-75012, France.ORCID https://orcid.org/0000-0001-9932-6438
Shéhanie UdugampolageUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.
Baptiste Libé-PhilippotUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0001-8283-804X
Talya C InbarUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.
Joanna SchwenkgrubUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Auditory System Dynamics and Multisensory Processing, Paris, F-75012, France.ORCID https://orcid.org/0000-0002-9695-9050
Carla Maria Barbosa SpinolaUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Cochlear Development and Therapeutic Perspectives, Paris, F-75012, France.ORCID https://orcid.org/0000-0001-8608-0723
Raphaël EtournayUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Cochlear Development and Therapeutic Perspectives, Paris, F-75012, France.ORCID https://orcid.org/0000-0002-2441-9274
Aziz El-AmraouiUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Progressive Sensory Disorders, Pathophysiology and Therapy, Paris, F-75012, France.ORCID https://orcid.org/0000-0003-2692-4984
Brice BathellierUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Auditory System Dynamics and Multisensory Processing, Paris, F-75012, France.ORCID https://orcid.org/0000-0001-9211-1960
Christine PetitUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Auditory Therapies Innovation Laboratory, Paris, F-75012, France.ORCID https://orcid.org/0000-0002-9069-002X
Boris GourévitchUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0001-6742-8739
Paul AvanLaboratoire de Biophysique Neurosensorielle, INSERM 1107, Université Clermont Auvergne, Clermont-Ferrand, F-63000, France.ORCID https://orcid.org/0000-0003-1054-1479
Nicolas MichalskiUniversité Paris Cité, Institut Pasteur, AP-HP, INSERM, CNRS, Fondation Pour l'Audition, Institut de l'Audition, IHU reConnect, Plasticity of Central Auditory Circuits, Paris, F-75012, France.ORCID https://orcid.org/0000-0002-1287-2709
Funding
Agence Nationale de la Recherche "AUDINNOVE" ANR-18-RHUS-0007Agence Nationale de la Recherche "FATIGAUDIT" ANR-21-CE34-0012Agence Nationale de la Recherche "LIFESENSES" ANR-10-LABX-65Agence Nationale de la Recherche, the France 2030 program ANR-23-IAHU-0003Agence Nationale de la Recherche "TIME-TO-EAR" ANR-23-CE17-0029European Molecular Biology Organization ALTF 852-2019Fondation Pour l'Audition FPAIDA02Fondation Pour l'Audition FPAIDA03Fondation Pour l'Audition FPAIDA05Fondation Pour l'Audition FPAIDA07Fondation Pour l'Audition RD-2023-1French Government Programme Investissements d'Avenir France BioImaging ANR-10-INSB-04-01Laboratoire d'Excellence "Integrative Biology of Emerging Infectious Diseases" ANR-10-LABX-62-IBEID"LIGHT4DEAF" ANR-15-RHUS-0001Sorbonne Université PhD Programthe Fondation pour la Recherche Medicale FDM201806005994the Institut Pasteur PTR618-23the Institut Pasteur - Paris University International Doctoral Programthe Marie Skłodowska-Curie initiative H2020-MSCA-IF-2017the Raimonde and Guy Strittmatter Foundation
6 · The paper itself
Abstract
Auditory neuropathies affect the spiral ganglion neurons of the auditory nerve or their synapses with the sensory hair cells, distorting the sound information transmitted from the ear to the brain. Deciphering the underlying pathophysiological mechanisms remains challenging owing to the diversity of spiral ganglion neuron subtypes and associated central auditory circuits. An auditory neuropathy mechanism is unraveled by investigating the origin of auditory hyperexcitability in a mouse model for hereditary congenital deafness. Otogl encodes the large Otogelin-like protein, which is related to secreted epithelial mucins and is implicated in the mechanical stimulation of cochlear outer hair cells. Heterozygous Otogl
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Deciphering Auditory Hyperexcitability in Otogl Mutant Mice Unravels an Auditory Neuropathy Mechanism. · full record | OpenQuestion